P83340 (EPIP1_EPIPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Major allergen Epi p 1 EC=3.4.21.- Alternative name(s): Allergen EpI n I4625* Allergen=Epi p 1
Organism	Epicoccum purpurascens (Soil fungus) (Epicoccum nigrum)
Taxonomic identifier	105696 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › dothideomyceta › Dothideomycetes › mitosporic Dothideomycetes › Epicoccum

Protein attributes

Sequence length	18 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has a serine protease activity.
Post-translational modification	Glycosylated. Ref.1
Allergenic properties	Causes an allergic reaction in human.
Mass spectrometry	Molecular mass is 33500 Da from positions 1 - ?. Determined by MALDI. Ref.1

Ontologies

Keywords
Disease	Allergen
Molecular function	Hydrolase Protease Serine protease
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	serine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›18	›18	Major allergen Epi p 1		PRO_0000086988
Experimental info
	Non-adjacent residues	12 – 13	2
	Non-terminal residue	18	1

Sequences

	Sequence		Length	Mass (Da)
	P83340 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 3EB607F66623CF3B	FASTA	18	1,952
	10 ADGIVAVELD TYRGSFXK

References

[1]

"Purification and characterization of a major cross-reactive allergen from Epicoccum purpurascens." Bisht V., Arora N., Singh B.P., Gaur S.N., Sridhara S. Int. Arch. Allergy Immunol. 133:217-224(2004) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE, GLYCOSYLATION, MASS SPECTROMETRY. Strain: 4625. Tissue: Mycelium and Spore.

Cross-references

3D structure databases
ModBase	Search...
Protein family/group databases
Allergome	3274. Epi p 1.0101. 853. Epi p 1.
MEROPS	S9G.113.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR019825. Lectin_legB_Mn/Ca_BS. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EPIP1_EPIPU

Accession

Primary (citable) accession number: P83340

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	June 1, 2002
Last modified:	November 16, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program