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P83246

- GST_ASADI

UniProt

P83246 - GST_ASADI

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Protein

Glutathione S-transferase

Gene
N/A
Organism
Asaphis dichotoma
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Has a strong specific activity toward 1-chloro-2,4-dinitrobenzene and ethacrynic acid.1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.1 Publication

Kineticsi

  1. KM=0.68 mM for 1-chloro-2,4-dinitrobenzene1 Publication
  2. KM=0.106 mM for glutathione1 Publication

Vmax=0.1446 mmol/min/mg enzyme toward CDNB1 Publication

Vmax=0.033 mmol/min/mg enzyme toward GSH1 Publication

pH dependencei

Optimum pH is 8.5 with 1-chloro-2,4-dinitrobenzene as substrate.1 Publication

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB
  2. protein homodimerization activity Source: UniProtKB

GO - Biological processi

  1. glutathione metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase (EC:2.5.1.18)
Alternative name(s):
GST class-sigma
adGST
OrganismiAsaphis dichotomaCurated
Taxonomic identifieri184428 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaHeteroconchiaVeneroidaTellinoideaPsammobiidaeAsaphis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›15›15Glutathione S-transferasePRO_0000185923Add
BLAST

Interactioni

Subunit structurei

Homodimer.1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the GST superfamily. Sigma family.By similarity

Sequencei

Sequence statusi: Fragment.

P83246-1 [UniParc]FASTAAdd to Basket

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        10 
PSYKLHYFDL RAAGE
Length:15
Mass (Da):1,767
Last modified:March 1, 2002 - v1
Checksum:iCB3E4BF92D3CB0B9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei15 – 1511 Publication

Mass spectrometryi

Molecular mass is 23138 Da from positions 1 - ?. Determined by MALDI. 1 Publication

Cross-referencesi

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Purification and characterization of a novel glutathione S-transferase from Asaphis dichotoma."
    Yang H.-L., Nie L.-J., Zhu S.-G., Zhou X.-W.
    Arch. Biochem. Biophys. 403:202-208(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, FUNCTION, SUBUNIT, MASS SPECTROMETRY, CIRCULAR DICHROISM ANALYSIS.
    Tissue: Gut and Liver.

Entry informationi

Entry nameiGST_ASADI
AccessioniPrimary (citable) accession number: P83246
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Miscellaneous

In A.dichotoma there are at least two isozymes of glutathione S-transferase.1 Publication

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3