P83155 (ALF_ANASL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Fructose-bisphosphate aldolase Short name=FBP aldolase Short name=FBPA EC=4.1.2.13 Alternative name(s): Fructose-1,6-bisphosphate aldolase
Organism	Anabaena sp. (strain L31)
Taxonomic identifier	29412 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	16 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. UniProtKB P29271
Cofactor	Binds 2 zinc ions per subunit. One is catalytic and the other provides a structural contribution By similarity.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. UniProtKB P29271
Subunit structure	Homodimer By similarity. UniProtKB P29271
Sequence similarities	Belongs to the class II fructose-bisphosphate aldolase family.

Ontologies

Keywords
Biological process	Glycolysis
Ligand	Metal-binding Zinc
Molecular function	Lyase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›16	›16	Fructose-bisphosphate aldolase		PRO_0000262929
Experimental info
	Non-terminal residue	16	1

Sequences

	Sequence		Length	Mass (Da)
	P83155 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 5D2670D9E4833A8B	FASTA	16	1,702
	10 ALVPLRLLLD HAAENG

References

[1]	Apte S.K., Uhlemann E., Schmid R., Altendorf K. Submitted (OCT-2001) to UniProtKB Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00109; UER00183.
Family and domain databases
PROSITE	PS00602. ALDOLASE_CLASS_II_1. Partial match. PS00806. ALDOLASE_CLASS_II_2. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALF_ANASL

Accession

Primary (citable) accession number: P83155

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	March 1, 2002
Last modified:	January 9, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program