Reviewed, UniProtKB/Swiss-Prot P83139 (AFP5_MALPA)

Names and origin

Protein names	Recommended name:     Antifungal protein 5 Alternative name(s):     CW-5
Organism	Malva parviflora (Little mallow) (Cheeseweed mallow)
Taxonomic identifier	145753 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Malvales › Malvaceae › Malvoideae › Malva

Protein attributes

Sequence length	38 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Possesses potent antifungal activity against F.graminearum but not P.infestans. Ref.1
Miscellaneous	Under low salt conditions, possesses potent antifungal activity but activity is drastically reduced under high salt conditions. Ref.1
Sequence similarities	Belongs to the plant LTP family.

Ontologies

Keywords
Molecular function	Antibiotic Antimicrobial Fungicide
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW defense response to fungus Ref.1 Inferred from direct assay. Source: UniProtKB killing of cells of another organism Inferred from electronic annotation. Source: UniProtKB-KW lipid transport Non-traceable author statement. Source: UniProtKB multicellular organismal development Ref.1 Non-traceable author statement. Source: UniProtKB xenobiotic metabolic process Ref.1 Inferred from direct assay. Source: UniProtKB
Molecular function	lipid binding Non-traceable author statement. Source: UniProtKB lipid transporter activity Non-traceable author statement. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›38	›38	Antifungal protein 5		PRO_0000153890
Experimental info
	Non-terminal residue	38	1

Sequences

	Sequence		Length	Mass (Da)
	P83139-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: C4D7F36913389784	FASTA	38	3,902
	10 20 30 ITCGQVTSQV AGCLSYLQRG GAPAPXXXXG IRNLXXMA

References

[1]	"Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora)." Wang X., Bunkers G.J., Walters M.R., Thoma R.S. Biochem. Biophys. Res. Commun. 282:1224-1228(2001) [PubMed: 11302747] [Abstract] Cited for: PROTEIN SEQUENCE, FUNCTION. Tissue: Seed.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
PROSITE	PS00597. PLANT_LTP. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AFP5_MALPA

Accession

Primary (citable) accession number: P83139

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2002
Last sequence update:	December 1, 2001
Last modified:	February 9, 2010
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)