Reviewed, UniProtKB/Swiss-Prot P83138 (AFP4_MALPA)

Names and origin

Protein names	Recommended name:     Antifungal protein 4 Alternative name(s):     CW-4
Organism	Malva parviflora (Little mallow) (Cheeseweed mallow)
Taxonomic identifier	145753 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Malvales › Malvaceae › Malvoideae › Malva

Protein attributes

Sequence length	37 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Possesses antifungal activity against P.infestans but not F.graminearum. Ref.1
Subcellular location	Secreted.
Miscellaneous	Antimicrobial activity is not affected by salt concentration.
Biophysicochemical properties	Temperature dependence: Thermostable. Still active after heating at 100 degrees Celsius for 20 minutes.

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Antibiotic Antimicrobial Fungicide
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW defense response to fungus Ref.1 Inferred from direct assay. Source: UniProtKB killing of cells of another organism Inferred from electronic annotation. Source: UniProtKB-KW multicellular organismal development Ref.1 Non-traceable author statement. Source: UniProtKB xenobiotic metabolic process Ref.1 Inferred from direct assay. Source: UniProtKB
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›37	›37	Antifungal protein 4		PRO_0000064483
Experimental info
	Non-terminal residue	37	1

Sequences

	Sequence		Length	Mass (Da)
	P83138-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 52293EEA2C77B6D6	FASTA	37	4,441
	10 20 30 DRQIDMEEQQ LEKLNKQDRX PGLRYAAKQQ MXTXRMG

References

[1]	"Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora)." Wang X., Bunkers G.J., Walters M.R., Thoma R.S. Biochem. Biophys. Res. Commun. 282:1224-1228(2001) [PubMed: 11302747] [Abstract] Cited for: PROTEIN SEQUENCE, FUNCTION. Tissue: Seed.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

AFP4_MALPA

Accession

Primary (citable) accession number: P83138

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2002
Last sequence update:	December 1, 2001
Last modified:	February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)