P83003 (CALR_ENTHI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Calreticulin
Organism	Entamoeba histolytica
Taxonomic identifier	5759 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Amoebozoa › Archamoebae › Entamoebidae › Entamoeba

Protein attributes

Sequence length	19 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER By similarity.
Subcellular location	Endoplasmic reticulum lumen By similarity.
Sequence similarities	Belongs to the calreticulin family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Ligand	Calcium Lectin Metal-binding Zinc
Molecular function	Chaperone
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	protein export from nucleus Inferred from sequence or structural similarity. Source: UniProtKB
Cellular_component	cytosol Inferred from sequence or structural similarity. Source: UniProtKB endoplasmic reticulum lumen Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›19	›19	Calreticulin		PRO_0000208521
Experimental info
	Non-terminal residue	19	1

Sequences

	Sequence		Length	Mass (Da)
	P83003 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: FC90BCAEFE1BA764	FASTA	19	2,489
	10 KVYFEETFEN GWKXIWSKW

References

[1]

"Calreticulin-like molecule in trophozoites of Entamoeba histolytica HM1:IMSS (SwissProt: accession P83003)." Gonzalez E., Rico G., Mendoza G., Ramos F., Garcia G., Moran P., Valadez A., Melendro E.I., Ximenez C. Am. J. Trop. Med. Hyg. 67:636-639(2002) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: ATCC 30459 / HM-1:IMSS.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00803. CALRETICULIN_1. Partial match. PS00804. CALRETICULIN_2. Partial match. PS00805. CALRETICULIN_REPEAT. Partial match. PS00014. ER_TARGET. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CALR_ENTHI

Accession

Primary (citable) accession number: P83003

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	October 1, 2001
Last modified:	June 13, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)