Reviewed, UniProtKB/Swiss-Prot P82954 (AHPC_ACICA)

Names and origin

Protein names

Recommended name:
    Alkyl hydroperoxide reductase subunit C
    EC=1.11.1.15
Alternative name(s):
    Peroxiredoxin
    Thioredoxin peroxidase
    Alkyl hydroperoxide reductase protein C22

Gene names

Name:

ahpC

Organism

Acinetobacter calcoaceticus

Taxonomic identifier

471 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	25 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Directly reduces organic hydroperoxides in its reduced dithiol form. UniProtKB P26427
Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
Subunit structure	Homodimer By similarity.
Induction	By oxidative stress, primary alcohols, monocyclic aromatics and heat shock. Ref.1
Sequence similarities	Belongs to the ahpC/TSA family. UniProtKB P19479

Ontologies

Keywords
Biological process	Stress response
Domain	Redox-active center
Molecular function	Oxidoreductase Peroxidase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peroxiredoxin activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›25	›25	Alkyl hydroperoxide reductase subunit C		PRO_0000135112
Experimental info
	Non-terminal residue	25	1

Sequences

	Sequence		Length	Mass (Da)
	P82954-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 7B3112366157F2D8	FASTA	25	2,836
	10 20 SLINTEVKPF QATAYHNGQF VEVNE

References

[1]	"Protein synthesis patterns in Acinetobacter calcoaceticus induced by phenol and catechol show specificities of responses to chemostress." Benndorf D., Loffhagen N., Babel W. FEMS Microbiol. Lett. 200:247-252(2001) [PubMed: 11425483] [Abstract] Cited for: PROTEIN SEQUENCE, INDUCTION. Strain: 69-V.

Cross-references

3D structure databases
HSSP	HSSP built from PDB template 1KYG based on UniProtKB P19479.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.15. 412.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

AHPC_ACICA

Accession

Primary (citable) accession number: P82954

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	October 1, 2001
Last modified:	January 20, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)