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P82933 (RT09_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S9, mitochondrial

Short name=MRP-S9
Short name=S9mt
Gene names
Name:MRPS9
Synonyms:RPMS9
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins By similarity.

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein S9P family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

revP046182EBI-721385,EBI-6164309From a different organism.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 39628S ribosomal protein S9, mitochondrialPRO_0000030655

Amino acid modifications

Modified residue2871N6-acetyllysine Ref.5

Natural variations

Natural variant131S → L.
Corresponds to variant rs13399067 [ dbSNP | Ensembl ].
VAR_047902

Sequences

Sequence LengthMass (Da)Tools
P82933 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: 74412E34F0926360

FASTA39645,835
        10         20         30         40         50         60 
MAAPCVSYGG AVSYRLLLWG RGSLARKQGL WKTAAPELQT NVRSQILRLR HTAFVIPKKN 

        70         80         90        100        110        120 
VPTSKRETYT EDFIKKQIEE FNIGKRHLAN MMGEDPETFT QEDIDRAIAY LFPSGLFEKR 

       130        140        150        160        170        180 
ARPVMKHPEQ IFPRQRAIQW GEDGRPFHYL FYTGKQSYYS LMHDVYGMLL NLEKHQSHLQ 

       190        200        210        220        230        240 
AKSLLPEKTV TRDVIGSRWL IKEELEEMLV EKLSDLDYMQ FIRLLEKLLT SQCGAAEEEF 

       250        260        270        280        290        300 
VQRFRRSVTL ESKKQLIEPV QYDEQGMAFS KSEGKRKTAK AEAIVYKHGS GRIKVNGIDY 

       310        320        330        340        350        360 
QLYFPITQDR EQLMFPFHFV DRLGKHDVTC TVSGGGRSAQ AGAIRLAMAK ALCSFVTEDE 

       370        380        390 
VEWMRQAGLL TTDPRVRERK KPGQEGARRK FTWKKR 

« Hide

References

« Hide 'large scale' references
[1]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]"The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present."
Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.
J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[5]"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-287, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[6]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC010884 Genomic DNA. No translation available.
AC107080 Genomic DNA. No translation available.
AC104655 Genomic DNA. No translation available.
CH471127 Genomic DNA. Translation: EAX01767.1.
BC057240 mRNA. Translation: AAH57240.1.
RefSeqNP_872578.1. NM_182640.2.
UniGeneHs.590900.

3D structure databases

ProteinModelPortalP82933.
SMRP82933. Positions 274-389.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122360. 43 interactions.
IntActP82933. 9 interactions.
MINTMINT-1379488.
STRING9606.ENSP00000258455.

PTM databases

PhosphoSiteP82933.

Polymorphism databases

DMDM218511769.

Proteomic databases

PaxDbP82933.
PRIDEP82933.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000258455; ENSP00000258455; ENSG00000135972.
GeneID64965.
KEGGhsa:64965.
UCSCuc002tcn.4. human.

Organism-specific databases

CTD64965.
GeneCardsGC02P105654.
HGNCHGNC:14501. MRPS9.
HPAHPA043476.
HPA048479.
MIM611975. gene.
neXtProtNX_P82933.
PharmGKBPA31028.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0103.
HOGENOMHOG000020877.
HOVERGENHBG023132.
InParanoidP82933.
KOK02996.
OMAARPVMKH.
OrthoDBEOG79PJPF.
PhylomeDBP82933.
TreeFamTF106154.

Gene expression databases

ArrayExpressP82933.
BgeeP82933.
CleanExHS_MRPS9.
GenevestigatorP82933.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000754. Ribosomal_S9.
IPR020574. Ribosomal_S9_CS.
[Graphical view]
PANTHERPTHR21569. PTHR21569. 1 hit.
PfamPF00380. Ribosomal_S9. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
PROSITEPS00360. RIBOSOMAL_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi64965.
NextBio67144.
PROP82933.
SOURCESearch...

Entry information

Entry nameRT09_HUMAN
AccessionPrimary (citable) accession number: P82933
Secondary accession number(s): Q6PG40
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: December 16, 2008
Last modified: April 16, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM