Reviewed, UniProtKB/Swiss-Prot P82930 (RT34_HUMAN)

Names and origin

Protein names

Recommended name:
    28S ribosomal protein S34, mitochondrial
      Short name=S34mt
      Short name=MRP-S34

Gene names

Name:

MRPS34

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subunit structure	Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
Subcellular location	Mitochondrion Ref.2.

Ontologies

Keywords
Cellular component	Mitochondrion
Coding sequence diversity	Polymorphism
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
DDX56	Q9NY93	1	EBI-1048516,EBI-372376
NFKBIL1	Q9UBC1	1	EBI-1048516,EBI-1043728

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	28S ribosomal protein S34, mitochondrial		PRO_0000087730
Natural variations
	Natural variant	33	1	L → I: dbSNP rs11552431.		VAR_052050

Sequences

	Sequence		Length	Mass (Da)
	P82930-1 [UniParc]. Last modified October 19, 2002. Version 2. Checksum: 58DC48FF63276060	FASTA	218	25,650
	10 20 30 40 50 60 MARKKVRPRL IAELARRVRA LREQLNRPRD SQLYAVDYET LTRPFSGRRL PVRAWADVRR 70 80 90 100 110 120 ESRLLQLLGR LPLFGLGRLV TRKSWLWQHD EPCYWRLTRV RPDYTAQNLD HGKAWGILTF 130 140 150 160 170 180 KGKTESEARE IEHVMYHDWR LVPKHEEEAF TAFTPAPEDS LASVPYPPLL RAMIIAERQK 190 200 210 NGDTSTEEPM LNVQRIRMEP WDYPAKQEDK GRAKGTPV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye.
[2]	"The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present." Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L. J. Biol. Chem. 276:19363-19374(2001) [PubMed: 11279123] [Abstract] Cited for: IDENTIFICATION.
[3]	Colinge J., Superti-Furga G., Bennett K.L. Submitted (OCT-2008) to UniProtKB Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC001182 mRNA. Translation: AAH01182.1.
IPI	IPI00169413.
RefSeq	NP_076425.1.
UniGene	Hs.157160
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P82930. 3 interactions.
STRING	P82930.
Proteomic databases
PRIDE	P82930.
Genome annotation databases
Ensembl	ENST00000397375; ENSP00000380531; ENSG00000074071; Homo sapiens. [Genome view]
GeneID	65993.
KEGG	hsa:65993.
NMPDR	fig|9606.3.peg.11507.
UCSC	uc002cmo.1. human.
Organism-specific databases
CTD	65993.
GeneCards	GC16M001761.
H-InvDB	HIX0012692.
HGNC	HGNC:16618. MRPS34.
MIM	611994. gene.
PharmGKB	PA31021.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	P82930.
Gene expression databases
ArrayExpress	P82930.
Bgee	P82930.
CleanEx	HS_MRPS34.
Genevestigator	P82930.
GermOnline	ENSG00000074071. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	67485.
SOURCE	Search...

Entry information

Entry name

RT34_HUMAN

Accession

Primary (citable) accession number: P82930
Secondary accession number(s): Q9BVI7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2002
Last sequence update:	October 19, 2002
Last modified:	December 15, 2009
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.