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Protein

Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic

Gene

CYP37

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Enzyme and pathway databases

BioCyciARA:AT3G15520-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic (EC:5.2.1.8)
Short name:
PPIase CYP37
Alternative name(s):
Rotamase CYP37
Thylakoid lumen PPIase of 38 kDa
Short name:
TLP38
Short name:
p38
Gene namesi
Name:CYP37
Ordered Locus Names:At3g15520
ORF Names:MJK13.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G15520.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: TAIR
  • chloroplast thylakoid Source: TAIR
  • chloroplast thylakoid lumen Source: UniProtKB-SubCell
  • chloroplast thylakoid membrane Source: TAIR
  • nucleus Source: GO_Central
  • thylakoid Source: TAIR
  • thylakoid lumen Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 6565ChloroplastSequence analysisAdd
BLAST
Transit peptidei66 – 11449Thylakoid1 PublicationAdd
BLAST
Chaini115 – 466352Peptidyl-prolyl cis-trans isomerase CYP37, chloroplasticPRO_0000025504Add
BLAST

Proteomic databases

PaxDbiP82869.
PRIDEiP82869.

Expressioni

Tissue specificityi

Aerial parts.1 Publication

Inductioni

Up-regulated by light. Down-regulated by dark.1 Publication

Gene expression databases

GenevisibleiP82869. AT.

Interactioni

Protein-protein interaction databases

BioGridi6125. 1 interaction.
STRINGi3702.AT3G15520.1.

Structurei

3D structure databases

ProteinModelPortaliP82869.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini278 – 466189PPIase cyclophilin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 PPIase cyclophilin-type domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IIEQ. Eukaryota.
COG0652. LUCA.
HOGENOMiHOG000012661.
InParanoidiP82869.
OMAiPANPNMK.
OrthoDBiEOG09360D4X.
PhylomeDBiP82869.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 2 hits.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P82869-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPLSSSTV VSHRLFFLHP SPLNRKFLFV KPKLPFNRTN SGDFRMRLHS
60 70 80 90 100
TSSKTGTKEL IHSCNSSIDS KLNTFEAGSK NLEKLVATIL IFVQVWSPLP
110 120 130 140 150
LFGLDSAYIS PAEAVLYSPD TKVPRTGELA LRRAIPANPS MKIIQASLED
160 170 180 190 200
ISYLLRIPQR KPYGTMESNV KKALKVAIDD KDKILASIPV DLKDKGSELY
210 220 230 240 250
TTLIDGKGGL QALITSIKKQ DPDKVSLGLA ASLDTVADLE LLQASGLSFL
260 270 280 290 300
LPQQYLNYPR LAGRGTVEIT IEKADGSTFS AEAGGDQRKS ATVQIVIDGY
310 320 330 340 350
SAPLTAGNFA KLVTSGAYDG AKLNTVNQAV ITEDGSGKVE SVSVPLEVMP
360 370 380 390 400
SGQFEPLYRT PLSVQDGELP VLPLSVYGAV AMAHSENSEE YSSPYQFFFY
410 420 430 440 450
LYDKRNSGLG GLSFDEGQFS VFGYTIAGKD ILGQIKTGDI IKSAKLIEGQ
460
DRLSLPVQNN NINEST
Length:466
Mass (Da):50,483
Last modified:June 12, 2007 - v3
Checksum:iF160CC1CF95D89E5
GO

Sequence cautioni

The sequence AAF35418 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence BAB02381 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022218 Genomic DNA. Translation: BAB02381.1. Sequence problems.
AC024081 Genomic DNA. Translation: AAF35418.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE75686.1.
BT025317 mRNA. Translation: ABF57273.1.
RefSeqiNP_188171.2. NM_112420.4.
UniGeneiAt.25187.
At.48665.
At.72746.

Genome annotation databases

EnsemblPlantsiAT3G15520.1; AT3G15520.1; AT3G15520.
GeneIDi820791.
GrameneiAT3G15520.1; AT3G15520.1; AT3G15520.
KEGGiath:AT3G15520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022218 Genomic DNA. Translation: BAB02381.1. Sequence problems.
AC024081 Genomic DNA. Translation: AAF35418.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE75686.1.
BT025317 mRNA. Translation: ABF57273.1.
RefSeqiNP_188171.2. NM_112420.4.
UniGeneiAt.25187.
At.48665.
At.72746.

3D structure databases

ProteinModelPortaliP82869.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi6125. 1 interaction.
STRINGi3702.AT3G15520.1.

Proteomic databases

PaxDbiP82869.
PRIDEiP82869.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G15520.1; AT3G15520.1; AT3G15520.
GeneIDi820791.
GrameneiAT3G15520.1; AT3G15520.1; AT3G15520.
KEGGiath:AT3G15520.

Organism-specific databases

TAIRiAT3G15520.

Phylogenomic databases

eggNOGiENOG410IIEQ. Eukaryota.
COG0652. LUCA.
HOGENOMiHOG000012661.
InParanoidiP82869.
OMAiPANPNMK.
OrthoDBiEOG09360D4X.
PhylomeDBiP82869.

Enzyme and pathway databases

BioCyciARA:AT3G15520-MONOMER.

Miscellaneous databases

PROiP82869.

Gene expression databases

GenevisibleiP82869. AT.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 2 hits.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCYP37_ARATH
AccessioniPrimary (citable) accession number: P82869
Secondary accession number(s): Q1JPN6, Q9LDZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: June 12, 2007
Last modified: September 7, 2016
This is version 108 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Both gene predictions and some EST data suggest that there may be an additional exon at the C-terminus, adding another 10 kDa to the protein.Curated

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.