Reviewed, UniProtKB/Swiss-Prot P82816 (MDHM_TOBAC)

Names and origin

Protein names	Recommended name:     Malate dehydrogenase, mitochondrial     EC=1.1.1.37
Organism	Nicotiana tabacum (Common tobacco)
Taxonomic identifier	4097 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH. Ref.1
Subunit structure	Homodimer By similarity. UniProtKB P17783
Subcellular location	Mitochondrion matrix By similarity.
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Cellular component	Mitochondrion
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	Malate dehydrogenase, mitochondrial		PRO_0000257976
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P82816-1 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 798C37750D955AE4	FASTA	15	1,472
	10 SSEAAPEEKV AILGA

References

[1]	Yamamoto Y., Asakura Y., Yamada H., Matsumoto H. Submitted (OCT-2000) to UniProtKB Cited for: PROTEIN SEQUENCE, CATALYTIC ACTIVITY. Strain: cv. Samsun.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.1.1.37. 298.
Family and domain databases
PROSITE	PS00068. MDH. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MDHM_TOBAC

Accession

Primary (citable) accession number: P82816

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	October 31, 2006
Last modified:	November 24, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)