P82772 (DF180_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative defensin-like protein 180

Alternative name(s):
Putative low-molecular-weight cysteine-rich protein 58
Short name=Protein LCR58

Gene names

Name:	LCR58
Ordered Locus Names:	At5g38317
ORF Names:	MSI17

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the DEFL family.
Caution	Contains 8 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family.

Ontologies

Keywords
Biological process	Plant defense
Cellular component	Secreted
Domain	Signal
Molecular function	Antimicrobial Fungicide
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	defense response to fungus Inferred from electronic annotation. Source: UniProtKB-KW killing of cells of other organism Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential
	Chain	27 – 127	101	Putative defensin-like protein 180		PRO_0000017296
Amino acid modifications
	Disulfide bond	29 ↔ 70		By similarity
	Disulfide bond	36 ↔ 55		By similarity
	Disulfide bond	39 ↔ 64		By similarity
	Disulfide bond	43 ↔ 66		By similarity
	Disulfide bond	81 ↔ 127		By similarity
	Disulfide bond	92 ↔ 112		By similarity
	Disulfide bond	97 ↔ 121		By similarity
	Disulfide bond	101 ↔ 123		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P82772 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 50E4B646530A52D8	FASTA	127	13,625
	10 20 30 40 50 60 MERITSLVFF ASFLIIFVSG VNQTRADSCD ESLGLCETCD ERCQAKHGPS CISKCDGEVG 70 80 90 100 110 120 MLSCTCTYEC GPPLPPKGNV CSGGTGMCSG KCPYKCCDTS CAQKYNGGRG FCNSFGNYNF CQCEYPC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones." Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S. DNA Res. 5:131-145(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response." Vanoosthuyse V., Miege C., Dumas C., Cock J.M. Plant Mol. Biol. 46:17-34(2001) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
[4]	"Genome organization of more than 300 defensin-like genes in Arabidopsis." Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A. Plant Physiol. 138:600-610(2005) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB011481 Genomic DNA. No translation available. CP002688 Genomic DNA. Translation: AED94295.1.
IPI	IPI00543937.
RefSeq	NP_001031979.1. NM_001036902.1.
UniGene	At.63335.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT5G38317.1-P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G38317.1; AT5G38317.1; AT5G38317.
GeneID	3771358.
KEGG	ath:AT5G38317.
Organism-specific databases
GeneFarm	4593. 429.
TAIR	At5g38317.
Phylogenomic databases
eggNOG	NOG288435.
HOGENOM	HOG000091148.
OMA	GPSCISK.
PhylomeDB	P82772.
ProtClustDB	CLSN2689682.
Gene expression databases
Genevestigator	P82772.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

DF180_ARATH

Accession

Primary (citable) accession number: P82772

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	October 1, 2002
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program