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Protein

Immune-induced peptide 4

Gene

IM4

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cell morphogenesis Source: FlyBase
  • defense response Source: UniProtKB
  • humoral immune response Source: FlyBase
  • innate immune response Source: UniProtKB-KW
  • response to bacterium Source: FlyBase
Complete GO annotation...

Keywords - Biological processi

Immunity, Innate immunity

Names & Taxonomyi

Protein namesi
Recommended name:
Immune-induced peptide 4
Short name:
DIM-4
Gene namesi
Name:IM4
ORF Names:CG15231
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0040653. IM4.

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB
  • extracellular space Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
PropeptideiPRO_000002149421 – 26Removed by a dipeptidylpeptidase2 Publications6
PeptideiPRO_000002149527 – 41Immune-induced peptide 4Add BLAST15

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41Threonine amide1

Keywords - PTMi

Amidation

Proteomic databases

PaxDbiP82705.
PRIDEiP82705.

Expressioni

Tissue specificityi

Hemolymph.

Inductioni

By bacterial infection.

Gene expression databases

BgeeiFBgn0040653.
ExpressionAtlasiP82705. baseline.
GenevisibleiP82705. DM.

Interactioni

Protein-protein interaction databases

BioGridi72555. 2 interactors.
DIPiDIP-21088N.
MINTiMINT-1603248.
STRINGi7227.FBpp0071487.

Structurei

3D structure databases

ProteinModelPortaliP82705.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiP82705.
KOiK20702.
PhylomeDBiP82705.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P82705-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MKFFQAAALL LAMFAALANA EPVPQPGTVL IQTDNTQYIR TG
Length:42
Mass (Da):4,523
Last modified:August 2, 2002 - v2
Checksum:iBDB1A618BD251003
GO

Mass spectrometryi

Molecular mass is 1720.9 Da from positions 27 - 41. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF46631.1.
AY070691 mRNA. Translation: AAL48162.1.
RefSeqiNP_001286648.1. NM_001299719.1.
NP_652295.1. NM_144038.3.
UniGeneiDm.6314.

Genome annotation databases

EnsemblMetazoaiFBtr0071559; FBpp0071487; FBgn0040653.
FBtr0345819; FBpp0311805; FBgn0040653.
GeneIDi50126.
KEGGidme:Dmel_CG15231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF46631.1.
AY070691 mRNA. Translation: AAL48162.1.
RefSeqiNP_001286648.1. NM_001299719.1.
NP_652295.1. NM_144038.3.
UniGeneiDm.6314.

3D structure databases

ProteinModelPortaliP82705.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi72555. 2 interactors.
DIPiDIP-21088N.
MINTiMINT-1603248.
STRINGi7227.FBpp0071487.

Proteomic databases

PaxDbiP82705.
PRIDEiP82705.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071559; FBpp0071487; FBgn0040653.
FBtr0345819; FBpp0311805; FBgn0040653.
GeneIDi50126.
KEGGidme:Dmel_CG15231.

Organism-specific databases

CTDi492981.
FlyBaseiFBgn0040653. IM4.

Phylogenomic databases

InParanoidiP82705.
KOiK20702.
PhylomeDBiP82705.

Miscellaneous databases

ChiTaRSiIM4. fly.
GenomeRNAii50126.
PROiP82705.

Gene expression databases

BgeeiFBgn0040653.
ExpressionAtlasiP82705. baseline.
GenevisibleiP82705. DM.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiIM04_DROME
AccessioniPrimary (citable) accession number: P82705
Secondary accession number(s): Q9W2Q9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: August 2, 2002
Last modified: November 30, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.