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Protein

Immune-induced peptide 4

Gene

IM4

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cell morphogenesis Source: FlyBase
  • defense response Source: UniProtKB
  • humoral immune response Source: FlyBase
  • innate immune response Source: UniProtKB-KW
  • response to bacterium Source: FlyBase

Keywordsi

Biological processImmunity, Innate immunity

Names & Taxonomyi

Protein namesi
Recommended name:
Immune-induced peptide 4
Short name:
DIM-4
Gene namesi
Name:IM4
ORF Names:CG15231
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0040653 IM4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
PropeptideiPRO_000002149421 – 26Removed by a dipeptidylpeptidase2 Publications6
PeptideiPRO_000002149527 – 41Immune-induced peptide 4Add BLAST15

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41Threonine amide2 Publications1

Keywords - PTMi

Amidation

Proteomic databases

PaxDbiP82705
PRIDEiP82705

Expressioni

Tissue specificityi

Hemolymph.

Inductioni

By bacterial infection.

Gene expression databases

BgeeiFBgn0040653
ExpressionAtlasiP82705 differential
GenevisibleiP82705 DM

Interactioni

Protein-protein interaction databases

BioGridi72555, 2 interactors
DIPiDIP-21088N
IntActiP82705, 2 interactors
STRINGi7227.FBpp0071487

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiP82705
KOiK20702
PhylomeDBiP82705

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P82705-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MKFFQAAALL LAMFAALANA EPVPQPGTVL IQTDNTQYIR TG
Length:42
Mass (Da):4,523
Last modified:August 2, 2002 - v2
Checksum:iBDB1A618BD251003
GO

Mass spectrometryi

Molecular mass is 1720.9 Da from positions 27 - 41. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF46631.1
AY070691 mRNA Translation: AAL48162.1
RefSeqiNP_001286648.1, NM_001299719.1
NP_652295.1, NM_144038.3
UniGeneiDm.6314

Genome annotation databases

EnsemblMetazoaiFBtr0071559; FBpp0071487; FBgn0040653
FBtr0345819; FBpp0311805; FBgn0040653
GeneIDi50126
KEGGidme:Dmel_CG15231

Similar proteinsi

Entry informationi

Entry nameiIM04_DROME
AccessioniPrimary (citable) accession number: P82705
Secondary accession number(s): Q9W2Q9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: August 2, 2002
Last modified: March 28, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health