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P82663

- RT25_HUMAN

UniProt

P82663 - RT25_HUMAN

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Protein
28S ribosomal protein S25, mitochondrial
Gene
MRPS25, RPMS25
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S25, mitochondrial
Short name:
MRP-S25
Short name:
S25mt
Gene namesi
Name:MRPS25
Synonyms:RPMS25
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:14511. MRPS25.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: HPA
  2. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31013.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 17317328S ribosomal protein S25, mitochondrial
PRO_0000087708Add
BLAST

Proteomic databases

MaxQBiP82663.
PaxDbiP82663.
PRIDEiP82663.

Expressioni

Gene expression databases

ArrayExpressiP82663.
BgeeiP82663.
CleanExiHS_MRPS25.
GenevestigatoriP82663.

Organism-specific databases

HPAiHPA043490.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein-protein interaction databases

BioGridi122180. 15 interactions.
IntActiP82663. 4 interactions.
MINTiMINT-8052188.
STRINGi9606.ENSP00000253686.

Structurei

3D structure databases

ProteinModelPortaliP82663.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG330435.
HOGENOMiHOG000007270.
HOVERGENiHBG002378.
InParanoidiP82663.
KOiK17404.
OMAiNGITHND.
OrthoDBiEOG7NCV4X.
PhylomeDBiP82663.
TreeFamiTF300292.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR007741. Ribosome/NADH_DH.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF05047. L51_S25_CI-B8. 1 hit.
[Graphical view]
SMARTiSM00916. L51_S25_CI-B8. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

P82663-1 [UniParc]FASTAAdd to Basket

« Hide

MPMKGRFPIR RTLQYLSQGN VVFKDSVKVM TVNYNTHGEL GEGARKFVFF    50
NIPQIQYKNP WVQIMMFKNM TPSPFLRFYL DSGEQVLVDV ETKSNKEIME 100
HIRKILGKNE ETLREEEEEK KQLSHPANFG PRKYCLRECI CEVEGQVPCP 150
SLVPLPKEMR GKYKAALKAD AQD 173
Length:173
Mass (Da):20,116
Last modified:March 1, 2001 - v1
Checksum:i78BB282C1539FA4C
GO

Sequence cautioni

The sequence BAB15723.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024702 mRNA. Translation: BAB14968.1.
AK024433 mRNA. Translation: BAB15723.1. Different initiation.
BC003590 mRNA. Translation: AAH03590.1.
CCDSiCCDS2622.1.
RefSeqiNP_071942.1. NM_022497.3.
UniGeneiHs.657764.
Hs.715617.

Genome annotation databases

EnsembliENST00000253686; ENSP00000253686; ENSG00000131368.
GeneIDi64432.
KEGGihsa:64432.
UCSCiuc003bzl.3. human.

Polymorphism databases

DMDMi13633894.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024702 mRNA. Translation: BAB14968.1 .
AK024433 mRNA. Translation: BAB15723.1 . Different initiation.
BC003590 mRNA. Translation: AAH03590.1 .
CCDSi CCDS2622.1.
RefSeqi NP_071942.1. NM_022497.3.
UniGenei Hs.657764.
Hs.715617.

3D structure databases

ProteinModelPortali P82663.
ModBasei Search...

Protein-protein interaction databases

BioGridi 122180. 15 interactions.
IntActi P82663. 4 interactions.
MINTi MINT-8052188.
STRINGi 9606.ENSP00000253686.

Polymorphism databases

DMDMi 13633894.

Proteomic databases

MaxQBi P82663.
PaxDbi P82663.
PRIDEi P82663.

Protocols and materials databases

DNASUi 64432.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000253686 ; ENSP00000253686 ; ENSG00000131368 .
GeneIDi 64432.
KEGGi hsa:64432.
UCSCi uc003bzl.3. human.

Organism-specific databases

CTDi 64432.
GeneCardsi GC03M015083.
HGNCi HGNC:14511. MRPS25.
HPAi HPA043490.
MIMi 611987. gene.
neXtProti NX_P82663.
PharmGKBi PA31013.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG330435.
HOGENOMi HOG000007270.
HOVERGENi HBG002378.
InParanoidi P82663.
KOi K17404.
OMAi NGITHND.
OrthoDBi EOG7NCV4X.
PhylomeDBi P82663.
TreeFami TF300292.

Miscellaneous databases

ChiTaRSi MRPS25. human.
GeneWikii MRPS25.
GenomeRNAii 64432.
NextBioi 66453.
PROi P82663.
SOURCEi Search...

Gene expression databases

ArrayExpressi P82663.
Bgeei P82663.
CleanExi HS_MRPS25.
Genevestigatori P82663.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR007741. Ribosome/NADH_DH.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF05047. L51_S25_CI-B8. 1 hit.
[Graphical view ]
SMARTi SM00916. L51_S25_CI-B8. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "Characterization of long cDNA clones from human adult spleen."
    Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O.
    DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.
  4. "A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins."
    Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.
    J. Biol. Chem. 275:32585-32591(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRT25_HUMAN
AccessioniPrimary (citable) accession number: P82663
Secondary accession number(s): Q9H7P5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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