Reviewed, UniProtKB/Swiss-Prot P82608 (GST82_DICLA)

Names and origin

Protein names	Recommended name:     Glutathione S-transferase 8.2       Short name=GST-8.2     EC=2.5.1.18 Alternative name(s):     GST class-alpha
Organism	Dicentrarchus labrax (European sea bass)
Taxonomic identifier	13489 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Percoidei › Moronidae › Dicentrarchus

Protein attributes

Sequence length	32 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Post-translational modification	The N-terminus is blocked.
Sequence similarities	Belongs to the GST superfamily. Alpha family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›32	›32	Glutathione S-transferase 8.2		PRO_0000185804
Experimental info
	Non-adjacent residues	16 – 17	2
	Non-terminal residue	1	1
	Non-terminal residue	32	1

Sequences

	Sequence		Length	Mass (Da)
	P82608-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 806C6F142ED3C3EA	FASTA	32	3,743
	10 20 30 MESIRWLLTV AQFDFDMKLV QSXAIVNYVA NK

References

[1]

"Purification and characterization of glutathione transferases from the sea bass (Dicentrarchus labrax) liver." Angelucci S., Sacchetta P., Moio P., Melino S., Petruzzelli R., Gervasi P., Di Ilio C. Arch. Biochem. Biophys. 373:435-441(2000) [PubMed: 10620369] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Liver.

Cross-references

3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	P82608.
Enzyme and pathway databases
BRENDA	2.5.1.18. 66764.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

GST82_DICLA

Accession

Primary (citable) accession number: P82608

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)