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Reviewed, UniProtKB/Swiss-Prot P82608 (GST82_DICLA)

Last modified June 16, 2009. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glutathione S-transferase 8.2
      Short name=GST-8.2
    EC=2.5.1.18
Alternative name(s):
    GST class-alpha
OrganismDicentrarchus labrax (European sea bass)
Taxonomic identifier13489 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiEuteleosteiNeoteleosteiAcanthomorphaAcanthopterygiiPercomorphaPerciformesPercoideiMoronidaeDicentrarchus

Protein attributes

Sequence length32 AA.
Sequence statusFragments.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subunit structure

Homodimer.

Subcellular location

Cytoplasm.

Post-translational modification

The N-terminus is blocked.

Sequence similarities

Belongs to the GST superfamily. Alpha family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglutathione transferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›32›32Glutathione S-transferase 8.2
PRO_0000185804

Experimental info

Non-adjacent residues16 – 172
Non-terminal residue11
Non-terminal residue321

Sequences

Sequence LengthMass (Da)Tools
P82608-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 806C6F142ED3C3EA

FASTA323,743
        10         20         30 
MESIRWLLTV AQFDFDMKLV QSXAIVNYVA NK 

« Hide

References

[1]"Purification and characterization of glutathione transferases from the sea bass (Dicentrarchus labrax) liver."
Angelucci S., Sacchetta P., Moio P., Melino S., Petruzzelli R., Gervasi P., Di Ilio C.
Arch. Biochem. Biophys. 373:435-441(2000) [PubMed: 10620369] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Liver.

Cross-references

3D structure databases

ModBaseSearch...

Phylogenomic databases

HOVERGENP82608.

Enzyme and pathway databases

BRENDA2.5.1.18. 66764.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameGST82_DICLA
AccessionPrimary (citable) accession number: P82608
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: October 1, 2000
Last modified: June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents