P82608 (GST82_DICLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Glutathione S-transferase 8.2 Short name=GST-8.2 EC=2.5.1.18 Alternative name(s): GST class-alpha
Organism	Dicentrarchus labrax (European seabass) (Morone labrax)
Taxonomic identifier	13489 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Neognathi › Neoteleostei › Eurypterygii › Ctenosquamata › Acanthomorpha › Euacanthomorpha › Holacanthopterygii › Acanthopterygii › Euacanthopterygii › Percomorpha › Perciformes › Percoidei › Moronidae › Dicentrarchus

Protein attributes

Sequence length	32 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Post-translational modification	The N-terminus is blocked.
Sequence similarities	Belongs to the GST superfamily. Alpha family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›32	›32	Glutathione S-transferase 8.2		PRO_0000185804
Experimental info
	Non-adjacent residues	16 – 17	2
	Non-terminal residue	1	1
	Non-terminal residue	32	1

Sequences

	Sequence		Length	Mass (Da)
	P82608 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 806C6F142ED3C3EA	FASTA	32	3,743
	10 20 30 MESIRWLLTV AQFDFDMKLV QSXAIVNYVA NK

References

[1]

"Purification and characterization of glutathione transferases from the sea bass (Dicentrarchus labrax) liver." Angelucci S., Sacchetta P., Moio P., Melino S., Petruzzelli R., Gervasi P., Di Ilio C. Arch. Biochem. Biophys. 373:435-441(2000) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Liver.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

GST82_DICLA

Accession

Primary (citable) accession number: P82608

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	October 1, 2000
Last modified:	April 3, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program