P82607 (GST67_DICLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Glutathione S-transferase 6.7 Short name=GST-6.7 EC=2.5.1.18 Alternative name(s): GST class-theta
Organism	Dicentrarchus labrax (European seabass) (Morone labrax)
Taxonomic identifier	13489 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Percoidei › Moronidae › Dicentrarchus

Protein attributes

Sequence length	54 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Post-translational modification	The N-terminus is blocked.
Sequence similarities	Belongs to the GST superfamily. Theta family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›54	›54	Glutathione S-transferase 6.7		PRO_0000185945
Experimental info
	Non-adjacent residues	37 – 38	2
	Non-terminal residue	1	1
	Non-terminal residue	54	1

Sequences

	Sequence		Length	Mass (Da)
	P82607 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 1BBF9327F1A53A5C	FASTA	54	6,142
	10 20 30 40 50 NPRGLPAFKH GNXVLNESYA XMYLESQFGS XGXLIPDADV IYYNWKVPEG ERHD

References

[1]

"Purification and characterization of glutathione transferases from the sea bass (Dicentrarchus labrax) liver." Angelucci S., Sacchetta P., Moio P., Melino S., Petruzzelli R., Gervasi P., Di Ilio C. Arch. Biochem. Biophys. 373:435-441(2000) [PubMed: 10620369] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Liver.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

GST67_DICLA

Accession

Primary (citable) accession number: P82607

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	October 1, 2000
Last modified:	May 31, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program