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P82607 (GST67_DICLA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase 6.7

Short name=GST-6.7
EC=2.5.1.18
Alternative name(s):
GST class-theta
OrganismDicentrarchus labrax (European seabass) (Morone labrax)
Taxonomic identifier13489 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPercomorphariaMoronidaeDicentrarchus

Protein attributes

Sequence length54 AA.
Sequence statusFragments.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subunit structure

Homodimer.

Subcellular location

Cytoplasm.

Post-translational modification

The N-terminus is blocked.

Sequence similarities

Belongs to the GST superfamily. Theta family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›54›54Glutathione S-transferase 6.7
PRO_0000185945

Experimental info

Non-adjacent residues37 – 382
Non-terminal residue11
Non-terminal residue541

Sequences

Sequence LengthMass (Da)Tools
P82607 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 1BBF9327F1A53A5C

FASTA546,142
        10         20         30         40         50 
NPRGLPAFKH GNXVLNESYA XMYLESQFGS XGXLIPDADV IYYNWKVPEG ERHD 

« Hide

References

[1]"Purification and characterization of glutathione transferases from the sea bass (Dicentrarchus labrax) liver."
Angelucci S., Sacchetta P., Moio P., Melino S., Petruzzelli R., Gervasi P., Di Ilio C.
Arch. Biochem. Biophys. 373:435-441(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Liver.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameGST67_DICLA
AccessionPrimary (citable) accession number: P82607
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families