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Protein

Cytochrome c oxidase polypeptide 2A

Gene

cbaD

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Hydrogen ion transport, Ion transport, Respiratory chain, Transport

Protein family/group databases

TCDBi3.D.4.2.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase polypeptide 2A (EC:1.9.3.1)
Alternative name(s):
Cytochrome c ba(3) subunit IIA
Cytochrome c oxidase polypeptide IIA
Cytochrome cba3 subunit 2A
Gene namesi
Name:cbaD
Ordered Locus Names:TTHA1133
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 34HelicalAdd BLAST31

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001839341 – 34Cytochrome c oxidase polypeptide 2AAdd BLAST34

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-formylmethionine1 Publication1

Keywords - PTMi

Formylation

Interactioni

Protein-protein interaction databases

IntActiP82543. 1 interactor.
STRINGi300852.TTHA1133.

Structurei

Secondary structure

134
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 32Combined sources27

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EHKX-ray2.40C2-34[»]
1XMEX-ray2.30C1-34[»]
2QPDX-ray3.25C1-34[»]
2QPEX-ray2.90C1-34[»]
3BVDX-ray3.37C1-34[»]
3EH3X-ray3.10C2-34[»]
3EH4X-ray2.90C2-34[»]
3EH5X-ray2.80C2-34[»]
3QJQX-ray2.90C1-34[»]
3QJRX-ray3.20C1-34[»]
3QJSX-ray2.80C1-34[»]
3QJTX-ray2.95C1-34[»]
3QJUX-ray2.90C1-34[»]
3QJVX-ray2.80C1-34[»]
3S33X-ray4.45C2-34[»]
3S38X-ray4.20C2-34[»]
3S39X-ray4.80C2-34[»]
3S3AX-ray4.25C2-34[»]
3S3BX-ray3.30C2-34[»]
3S3CX-ray4.00C2-34[»]
3S3DX-ray3.75C2-34[»]
3S8FX-ray1.80C1-34[»]
3S8GX-ray1.80C1-34[»]
4FA7X-ray2.50C1-34[»]
4FAAX-ray2.80C1-34[»]
4G70X-ray2.60C1-34[»]
4G71X-ray2.90C1-34[»]
4G72X-ray3.19C1-34[»]
4G7QX-ray2.60C1-34[»]
4G7RX-ray3.05C1-34[»]
4G7SX-ray2.00C1-34[»]
4GP4X-ray2.80C1-34[»]
4GP5X-ray2.70C1-34[»]
4GP8X-ray2.80C1-34[»]
4N4YX-ray2.90C1-34[»]
ProteinModelPortaliP82543.
SMRiP82543.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP82543.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiIPR012538. Cyt_c_oxidase_su2a.
[Graphical view]
PfamiPF08113. CoxIIa. 1 hit.
[Graphical view]
SUPFAMiSSF81473. SSF81473. 1 hit.

Sequencei

Sequence statusi: Complete.

P82543-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
MEEKPKGALA VILVLTLTIL VFWLGVYAVF FARG
Length:34
Mass (Da):3,767
Last modified:March 1, 2001 - v2
Checksum:iF473EB7D0B179FBB
GO

Mass spectrometryi

Molecular mass is 3794.6 Da from positions 1 - 34. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70956.1.
RefSeqiWP_008632613.1. NC_006461.1.
YP_144399.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70956; BAD70956; BAD70956.
GeneIDi3168186.
KEGGittj:TTHA1133.
PATRICi23957225. VBITheThe93045_1112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70956.1.
RefSeqiWP_008632613.1. NC_006461.1.
YP_144399.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EHKX-ray2.40C2-34[»]
1XMEX-ray2.30C1-34[»]
2QPDX-ray3.25C1-34[»]
2QPEX-ray2.90C1-34[»]
3BVDX-ray3.37C1-34[»]
3EH3X-ray3.10C2-34[»]
3EH4X-ray2.90C2-34[»]
3EH5X-ray2.80C2-34[»]
3QJQX-ray2.90C1-34[»]
3QJRX-ray3.20C1-34[»]
3QJSX-ray2.80C1-34[»]
3QJTX-ray2.95C1-34[»]
3QJUX-ray2.90C1-34[»]
3QJVX-ray2.80C1-34[»]
3S33X-ray4.45C2-34[»]
3S38X-ray4.20C2-34[»]
3S39X-ray4.80C2-34[»]
3S3AX-ray4.25C2-34[»]
3S3BX-ray3.30C2-34[»]
3S3CX-ray4.00C2-34[»]
3S3DX-ray3.75C2-34[»]
3S8FX-ray1.80C1-34[»]
3S8GX-ray1.80C1-34[»]
4FA7X-ray2.50C1-34[»]
4FAAX-ray2.80C1-34[»]
4G70X-ray2.60C1-34[»]
4G71X-ray2.90C1-34[»]
4G72X-ray3.19C1-34[»]
4G7QX-ray2.60C1-34[»]
4G7RX-ray3.05C1-34[»]
4G7SX-ray2.00C1-34[»]
4GP4X-ray2.80C1-34[»]
4GP5X-ray2.70C1-34[»]
4GP8X-ray2.80C1-34[»]
4N4YX-ray2.90C1-34[»]
ProteinModelPortaliP82543.
SMRiP82543.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP82543. 1 interactor.
STRINGi300852.TTHA1133.

Protein family/group databases

TCDBi3.D.4.2.1. the proton-translocating cytochrome oxidase (cox) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70956; BAD70956; BAD70956.
GeneIDi3168186.
KEGGittj:TTHA1133.
PATRICi23957225. VBITheThe93045_1112.

Miscellaneous databases

EvolutionaryTraceiP82543.

Family and domain databases

InterProiIPR012538. Cyt_c_oxidase_su2a.
[Graphical view]
PfamiPF08113. CoxIIa. 1 hit.
[Graphical view]
SUPFAMiSSF81473. SSF81473. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOXA_THET8
AccessioniPrimary (citable) accession number: P82543
Secondary accession number(s): Q5SJ81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.