P82534 (NLTP1_PRUDO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Non-specific lipid-transfer protein 1 Short name=LTP 1 Alternative name(s): Major allergen Pru d 3 Allergen=Pur d 3
Organism	Prunus domestica (Garden plum)
Taxonomic identifier	3758 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Rosales › Rosaceae › Maloideae › Amygdaleae › Prunus

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
Allergenic properties	Causes an allergic reaction in human. Binds to IgE.
Sequence similarities	Belongs to the plant LTP family.

Ontologies

Keywords
Biological process	Transport
Disease	Allergen
Ligand	Lipid-binding
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	lipid transport Inferred from electronic annotation. Source: InterPro
Molecular function	lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Non-specific lipid-transfer protein 1		PRO_0000153879
Amino acid modifications
	Disulfide bond	3 ↔ 50		By similarity
	Disulfide bond	13 ↔ 27		By similarity
	Disulfide bond	28 ↔ 73		By similarity
	Disulfide bond	48 ↔ 87		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P82534 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: F2165C2465CD0377	FASTA	91	9,175
	10 20 30 40 50 60 ITCGQVSSNL APCINYVKGG GAVPPACCNG IRNVNNLART TADRRAACNC LKQLSGSIPG 70 80 90 VNPNNAAALP GKCGVNVPYK ISASTNCATV K

References

[1]	"Characterization of the major allergen of plum as a lipid transfer protein." Pastorello E.A., Farioli L., Pravettoni V., Giuffrida M.G., Ortolani C., Fortunato D., Trambaioli C., Scibola E., Calamari A.M., Robino A.M., Conti A. J. Chromatogr. B 756:95-103(2001) [PubMed: 11419731] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Peelings.
+	Additional computationally mapped references.

Cross-references

3D structure databases
ProteinModelPortal	P82534.
SMR	P82534. Positions 1-91.
ModBase	Search...
Protein family/group databases
Allergome	3451. Pru d 3.0101. 601. Pru d 3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR016140. Bifunc_inhib/LTP/seed_store. IPR013770. Lipid_transfer_prot_hlx-dom. IPR003612. LTP/seed_store/tryp_amyl_inhib. IPR000528. Plant_LTP. [Graphical view]
Gene3D	G3DSA:1.10.110.10. LPT_helical. 1 hit.
Pfam	PF00234. Tryp_alpha_amyl. 1 hit. [Graphical view]
PRINTS	PR00382. LIPIDTRNSFER.
SMART	SM00499. AAI. 1 hit. [Graphical view]
SUPFAM	SSF47699. Bifunc_inhib/LTP/seed_store. 1 hit.
PROSITE	PS00597. PLANT_LTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NLTP1_PRUDO

Accession

Primary (citable) accession number: P82534

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	October 19, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program