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Protein

Superoxide reductase

Gene

sorA

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.1 Publication

Catalytic activityi

Reduced rubredoxin + superoxide + 2 H+ = oxidized rubredoxin + H2O2.1 Publication

Cofactori

Fe cation1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi14Iron1
Metal bindingi16Iron1
Metal bindingi41Iron1
Metal bindingi47Iron1
Metal bindingi111Iron1
Metal bindingi114Iron1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BRENDAi1.15.1.2. 5243.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide reductase (EC:1.15.1.2)
Short name:
SOR
Gene namesi
Name:sorA
Ordered Locus Names:PF1281
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001408731 – 124Superoxide reductaseAdd BLAST124

Proteomic databases

PRIDEiP82385.

Interactioni

Subunit structurei

Homotetramer.

Protein-protein interaction databases

STRINGi186497.PF1281.

Structurei

Secondary structure

1124
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 5Combined sources4
Turni11 – 13Combined sources3
Beta strandi19 – 25Combined sources7
Beta strandi28 – 35Combined sources8
Beta strandi37 – 39Combined sources3
Beta strandi44 – 47Combined sources4
Beta strandi49 – 58Combined sources10
Beta strandi65 – 72Combined sources8
Beta strandi91 – 98Combined sources8
Beta strandi103 – 111Combined sources9
Turni112 – 114Combined sources3
Beta strandi115 – 123Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DO6X-ray2.00A/B1-124[»]
1DQIX-ray1.70A/B/C/D1-124[»]
1DQKX-ray2.00A/B/C/D1-124[»]
ProteinModelPortaliP82385.
SMRiP82385.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP82385.

Family & Domainsi

Sequence similaritiesi

Belongs to the desulfoferrodoxin family.Curated

Phylogenomic databases

eggNOGiarCOG02146. Archaea.
COG2033. LUCA.
HOGENOMiHOG000008862.
KOiK05919.
OMAiHVPVIEY.

Family and domain databases

InterProiIPR002742. Desulfoferrodoxin_Fe-bd_dom.
[Graphical view]
PfamiPF01880. Desulfoferrodox. 1 hit.
[Graphical view]
SUPFAMiSSF49367. SSF49367. 1 hit.
TIGRFAMsiTIGR00332. neela_ferrous. 1 hit.

Sequencei

Sequence statusi: Complete.

P82385-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISETIRSGD WKGEKHVPVI EYEREGELVK VKVQVGKEIP HPNTTEHHIR
60 70 80 90 100
YIELYFLPEG ENFVYQVGRV EFTAHGESVN GPNTSDVYTE PIAYFVLKTK
110 120
KKGKLYALSY CNIHGLWENE VTLE
Length:124
Mass (Da):14,324
Last modified:May 1, 2000 - v1
Checksum:iEDD92C7E501C8048
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF156097 Genomic DNA. Translation: AAF03229.1.
AE009950 Genomic DNA. Translation: AAL81405.1.
PIRiT44571.
RefSeqiWP_011012425.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81405; AAL81405; PF1281.
GeneIDi1469154.
KEGGipfu:PF1281.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF156097 Genomic DNA. Translation: AAF03229.1.
AE009950 Genomic DNA. Translation: AAL81405.1.
PIRiT44571.
RefSeqiWP_011012425.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DO6X-ray2.00A/B1-124[»]
1DQIX-ray1.70A/B/C/D1-124[»]
1DQKX-ray2.00A/B/C/D1-124[»]
ProteinModelPortaliP82385.
SMRiP82385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF1281.

Proteomic databases

PRIDEiP82385.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL81405; AAL81405; PF1281.
GeneIDi1469154.
KEGGipfu:PF1281.

Phylogenomic databases

eggNOGiarCOG02146. Archaea.
COG2033. LUCA.
HOGENOMiHOG000008862.
KOiK05919.
OMAiHVPVIEY.

Enzyme and pathway databases

BRENDAi1.15.1.2. 5243.

Miscellaneous databases

EvolutionaryTraceiP82385.

Family and domain databases

InterProiIPR002742. Desulfoferrodoxin_Fe-bd_dom.
[Graphical view]
PfamiPF01880. Desulfoferrodox. 1 hit.
[Graphical view]
SUPFAMiSSF49367. SSF49367. 1 hit.
TIGRFAMsiTIGR00332. neela_ferrous. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSOR_PYRFU
AccessioniPrimary (citable) accession number: P82385
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: November 2, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.