Reviewed,
UniProtKB/Swiss-Prot P82385 (SOR_PYRFU)
Last modified
December 15, 2009.
Version 68.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Superoxide reductase Short name=SOR EC=1.15.1.2 | ||||
| Gene names |
| ||||
| Organism | Pyrococcus furiosus [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 2261 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus |
Protein attributes
| Sequence length | 124 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide. |
| Catalytic activity | Reduced rubredoxin + superoxide + 2 H+ = rubredoxin + H2O2. |
| Cofactor | Iron. |
| Subunit structure | Homotetramer. |
| Sequence similarities | Belongs to the desulfoferrodoxin family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Transport |
| Ligand | Iron Metal-binding |
| Molecular function | Oxidoreductase |
| Technical term | 3D-structure Complete proteome |
| Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide reductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||||||||||||||||||||
Molecule processing | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 124 | 124 | Superoxide reductase | PRO_0000140873 | |||||||||||||||||||||||||
Sites | |||||||||||||||||||||||||||||
| Metal binding | 14 | 1 | Iron | ||||||||||||||||||||||||||
| Metal binding | 16 | 1 | Iron | ||||||||||||||||||||||||||
| Metal binding | 41 | 1 | Iron | ||||||||||||||||||||||||||
| Metal binding | 47 | 1 | Iron | ||||||||||||||||||||||||||
| Metal binding | 111 | 1 | Iron | ||||||||||||||||||||||||||
| Metal binding | 114 | 1 | Iron | ||||||||||||||||||||||||||
Secondary structure | |||||||||||||||||||||||||||||
Helix Strand Turn | |||||||||||||||||||||||||||||
| Helix | 2 – 5 | 4 | |||||||||||||||||||||||||||
| Beta strand | 19 – 25 | 7 | |||||||||||||||||||||||||||
| Beta strand | 28 – 35 | 8 | |||||||||||||||||||||||||||
| Beta strand | 37 – 39 | 3 | |||||||||||||||||||||||||||
| Beta strand | 44 – 47 | 4 | |||||||||||||||||||||||||||
| Beta strand | 49 – 58 | 10 | |||||||||||||||||||||||||||
| Beta strand | 65 – 72 | 8 | |||||||||||||||||||||||||||
| Beta strand | 91 – 98 | 8 | |||||||||||||||||||||||||||
| Beta strand | 103 – 111 | 9 | |||||||||||||||||||||||||||
| Turn | 112 – 114 | 3 | |||||||||||||||||||||||||||
| Beta strand | 115 – 123 | 9 | |||||||||||||||||||||||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Anaerobic microbes: oxygen detoxification without superoxide dismutase." Jenney F.E. Jr., Verhagen M.F.J.M., Cui X., Adams M.W.W. Science 286:306-309(1999) [PubMed: 10514376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1. |
| [2] | "The complete sequence of the Pyrococcus furiosus genome." Weiss R.B., Dunn D.M., Robb F.T., Brown J.R. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1. |
| [3] | "Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states." Yeh A.P., Hu Y., Jenney F.E. Jr., Adams M.W.W., Rees D.C. Biochemistry 39:2499-2508(2000) [PubMed: 10704199] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS). |
Cross-references
Sequence databases | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF156097 Genomic DNA. Translation: AAF03229.1. AE009950 Genomic DNA. Translation: AAL81405.1. | |||||||||||||||||||||||||
| PIR | T44571. | ||||||||||||||||||||||||
| RefSeq | NP_579010.1. | ||||||||||||||||||||||||
3D structure databases | |||||||||||||||||||||||||
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| ModBase | Search... | ||||||||||||||||||||||||
Genome annotation databases | |||||||||||||||||||||||||
| GeneID | 1469154. | ||||||||||||||||||||||||
| GenomeReviews | Gene locus PF1281 in contig AE009950_GR. | ||||||||||||||||||||||||
| KEGG | pfu:PF1281. | ||||||||||||||||||||||||
| NMPDR | fig|186497.1.peg.1325. | ||||||||||||||||||||||||
Organism-specific databases | |||||||||||||||||||||||||
| CMR | Search... | ||||||||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||||||||
| HOGENOM | HBG541098. | ||||||||||||||||||||||||
| OMA | EHHIAWI. | ||||||||||||||||||||||||
Enzyme and pathway databases | |||||||||||||||||||||||||
| BRENDA | 1.15.1.2. 321. | ||||||||||||||||||||||||
Family and domain databases | |||||||||||||||||||||||||
| InterPro | IPR002742. Desulfoferrodoxin_Fe-bd. [Graphical view] | ||||||||||||||||||||||||
| Pfam | PF01880. Desulfoferrodox. 1 hit. [Graphical view] | ||||||||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||||||||
Entry information
| Entry name | SOR_PYRFU | ||||||||
| Accession | Primary (citable) accession number: P82385 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with


