##gff-version 3 P82228 UniProtKB Peptide 1 37 . . . ID=PRO_0000044998;Note=Lambda-hexatoxin-Hv1c;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10881200;Dbxref=PMID:10881200 P82228 UniProtKB Site 2 2 . . . Note=Important for the neurotoxic activity P82228 UniProtKB Site 8 8 . . . Note=Critical for the neurotoxic activity P82228 UniProtKB Site 9 9 . . . Note=Critical for the neurotoxic activity P82228 UniProtKB Site 13 13 . . . Note=Critical for the neurotoxic activity P82228 UniProtKB Site 14 14 . . . Note=Critical for the neurotoxic activity P82228 UniProtKB Site 29 29 . . . Note=Important for the neurotoxic activity P82228 UniProtKB Site 31 31 . . . Note=Critical for the neurotoxic activity P82228 UniProtKB Disulfide bond 3 17 . . . Ontology_term=ECO:0000269,ECO:0000312;evidence=ECO:0000269|PubMed:10881200,ECO:0000312|PDB:1DL0;Dbxref=PMID:10881200 P82228 UniProtKB Disulfide bond 10 22 . . . Ontology_term=ECO:0000269,ECO:0000312;evidence=ECO:0000269|PubMed:10881200,ECO:0000312|PDB:1DL0;Dbxref=PMID:10881200 P82228 UniProtKB Disulfide bond 13 14 . . . Ontology_term=ECO:0000269,ECO:0000312;evidence=ECO:0000269|PubMed:10881200,ECO:0000312|PDB:1DL0;Dbxref=PMID:10881200 P82228 UniProtKB Disulfide bond 16 32 . . . Ontology_term=ECO:0000269,ECO:0000312;evidence=ECO:0000269|PubMed:10881200,ECO:0000312|PDB:1DL0;Dbxref=PMID:10881200 P82228 UniProtKB Mutagenesis 1 2 . . . Note=73-fold decrease in toxicity to flies. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12220722;Dbxref=PMID:12220722 P82228 UniProtKB Mutagenesis 1 1 . . . Note=No change in toxicity. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12220722;Dbxref=PMID:12220722 P82228 UniProtKB Mutagenesis 2 2 . . . Note=7-fold decrease in toxicity to flies. I->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 8 8 . . . Note=98-fold decrease in toxicity to flies. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 8 8 . . . Note=270-fold decrease in toxicity to flies. R->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 9 9 . . . Note=269-fold decrease in toxicity to flies. P->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 13 14 . . . Note=423-fold decrease in toxicity to flies. CC->SS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 29 29 . . . Note=13-fold decrease in toxicity to flies. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 31 31 . . . Note=162-fold decrease in toxicity to flies. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 31 31 . . . Note=1.8-fold decrease in toxicity to flies. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11937509;Dbxref=PMID:11937509 P82228 UniProtKB Mutagenesis 35 37 . . . Note=No change in toxicity to flies. Missing P82228 UniProtKB Mutagenesis 36 37 . . . Note=No change in toxicity. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12220722;Dbxref=PMID:12220722 P82228 UniProtKB Beta strand 20 24 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1DL0 P82228 UniProtKB Beta strand 30 34 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1DL0