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P82141 (DLP3_ORNAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Defensin-like peptide 3

Short name=DLP-3
OrganismOrnithorhynchus anatinus (Duckbill platypus) [Reference proteome]
Taxonomic identifier9258 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus

Protein attributes

Sequence length38 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Does not show antimicrobial, myotoxic, hemolytic and cell-promoting activities. Ref.1

Subcellular location

Secreted Ref.1.

Tissue specificity

Produced by the crural gland and detected in venom from the spur located on each male hind leg. Ref.1

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionToxin
   PTMDisulfide bond
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from expression pattern Ref.1. Source: UniProtKB

   Cellular_componentextracellular region

Inferred from direct assay Ref.1. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Peptide1 – 3838Defensin-like peptide 3
PRO_0000044773

Amino acid modifications

Disulfide bond13 ↔ 29 By similarity

Sequences

Sequence LengthMass (Da)Tools
P82141 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 4B2D1C6BB407F3DF

FASTA384,721
        10         20         30 
FEMQYCWSHS GVCRDKSERN NKPMAWTYCE NRQKKCEF 

« Hide

References

[1]"Solution structure of a defensin-like peptide from platypus venom."
Torres A.M., Wang X., Fletcher J.I., Alewood D., Alewood P.F., Smith R., Simpson R.J., Nicholson G.M., Sutherland S.K., Gallagher C.H., King G.F., Kuchel P.W.
Biochem. J. 341:785-794(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
Tissue: Venom and Venom gland.

Web resources

Protein Spotlight

Platypus poison - Issue 29 of December 2002

Cross-references

3D structure databases

ProteinModelPortalP82141.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR012553. Defensin_3.
[Graphical view]
PfamPF08131. Defensin_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDLP3_ORNAN
AccessionPrimary (citable) accession number: P82141
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program
Annotation programChordata Protein Annotation Program

Relevant documents

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries