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P81943

- ALL5_APIGR

UniProt

P81943 - ALL5_APIGR

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Protein

Allergen Api g 5

Gene
N/A
Organism
Apium graveolens (Celery)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Cofactori

FAD.By similarity

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW

GO - Biological processi

  1. type I hypersensitivity Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Api g 5
Alternative name(s):
Allergen: Api g 5
OrganismiApium graveolens (Celery)
Taxonomic identifieri4045 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsApialesApiaceaeApioideaeapioid supercladeApieaeApium

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE. The glycan moiety seems to constitute the relevant allergenic epitope.2 Publications

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3087. Api g 5.0101.
44. Api g 5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›86›86Allergen Api g 5PRO_0000128175Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi62 – 621N-linked (GlcNAc...)1 Publication

Post-translational modificationi

Carries MUXF and MMXF, two complex N-linked glycans with alpha-1,3-fucose and beta-1,2-xylose residues in their structures. MMXF is added to Asn-62.1 Publication

Keywords - PTMi

Glycoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.Sequence Analysis

Sequencei

Sequence statusi: Fragments.

P81943-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LPNPSGFVTC LSSISKSVYT PAINLKAVIA DPVAKTAVVQ AGATLGEVYY
60 70 80
XIIYARVLWV GNTTQKLEWI RSLHDYQSSF FPFFSA
Length:86
Mass (Da):9,441
Last modified:July 25, 2003 - v3
Checksum:i09F5C64FA7ACD452
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-adjacent residuesi22 – 2321 Publication
Non-adjacent residuesi52 – 5321 Publication
Non-adjacent residuesi76 – 7721 Publication
Non-terminal residuei86 – 8611 Publication

Cross-referencesi

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 3087. Api g 5.0101.
44. Api g 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. Cited for: PROTEIN SEQUENCE OF 1-18, ALLERGEN.
    Tissue: Tuber1 Publication.
  2. "Cross-reactive N-glycans of Api g 5, a high molecular weight glycoprotein allergen from celery, are required for immunoglobulin E binding and activation of effector cells from allergic patients."
    Bublin M., Radauer C., Wilson I.B.H., Kraft D., Scheiner O., Breiteneder H., Hoffmann-Sommergruber K.
    FASEB J. 17:1697-1699(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 19-86, SEQUENCE REVISION, GLYCOSYLATION, ALLERGEN.
    Tissue: Tuber1 Publication.

Entry informationi

Entry nameiALL5_APIGR
AccessioniPrimary (citable) accession number: P81943
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: July 25, 2003
Last modified: October 1, 2014
This is version 40 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

The order of the peptides shown is unknown.1 Publication

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3