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Protein

Defensin-1

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Possesses antifungal activity sensitive to inorganic cations.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-1
Alternative name(s):
Antifungal protein Psd1
Defense-related peptide 1
OrganismiPisum sativum (Garden pea)
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000742421 – 46Defensin-1Add BLAST46

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi3 ↔ 461 Publication
Disulfide bondi14 ↔ 351 Publication
Disulfide bondi20 ↔ 401 Publication
Disulfide bondi24 ↔ 421 Publication

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Epidermis and vascular bundles of pods, stems, roots, leaves and wet or dry seeds.

Developmental stagei

Mature seed in dormancy.

Structurei

Secondary structure

146
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 6Combined sources5
Beta strandi8 – 10Combined sources3
Helixi17 – 27Combined sources11
Beta strandi33 – 36Combined sources4
Beta strandi39 – 45Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JKZNMR-A1-46[»]
2IIWmodel-A1-46[»]
2IJ1model-A1-46[»]
2IJTmodel-A1-46[»]
2IJUmodel-A1-46[»]
2IJVmodel-A1-46[»]
2IJWmodel-A1-46[»]
2IKLmodel-A1-46[»]
2IKMmodel-A1-46[»]
2IKNmodel-A1-46[»]
2IKPmodel-A1-46[»]
2IKRmodel-A1-46[»]
2IKTmodel-A1-46[»]
2IKVmodel-A1-46[»]
2IKWmodel-A1-46[»]
2IKXmodel-A1-46[»]
2IKYmodel-A1-46[»]
2IKZmodel-A1-46[»]
2IL0model-A1-46[»]
2ILCmodel-A1-46[»]
2ILDmodel-A1-46[»]
2ILEmodel-A1-46[»]
2ILFmodel-A1-46[»]
2ILGmodel-A1-46[»]
2ILHmodel-A1-46[»]
2ILJmodel-A1-46[»]
ProteinModelPortaliP81929.
SMRiP81929.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP81929.

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P81929-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
KTCEHLADTY RGVCFTNASC DDHCKNKAHL ISGTCHNWKC FCTQNC
Length:46
Mass (Da):5,209
Last modified:March 5, 2002 - v2
Checksum:i12B4ABCF0A6701FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti43T → G AA sequence (PubMed:11697857).Curated1

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JKZNMR-A1-46[»]
2IIWmodel-A1-46[»]
2IJ1model-A1-46[»]
2IJTmodel-A1-46[»]
2IJUmodel-A1-46[»]
2IJVmodel-A1-46[»]
2IJWmodel-A1-46[»]
2IKLmodel-A1-46[»]
2IKMmodel-A1-46[»]
2IKNmodel-A1-46[»]
2IKPmodel-A1-46[»]
2IKRmodel-A1-46[»]
2IKTmodel-A1-46[»]
2IKVmodel-A1-46[»]
2IKWmodel-A1-46[»]
2IKXmodel-A1-46[»]
2IKYmodel-A1-46[»]
2IKZmodel-A1-46[»]
2IL0model-A1-46[»]
2ILCmodel-A1-46[»]
2ILDmodel-A1-46[»]
2ILEmodel-A1-46[»]
2ILFmodel-A1-46[»]
2ILGmodel-A1-46[»]
2ILHmodel-A1-46[»]
2ILJmodel-A1-46[»]
ProteinModelPortaliP81929.
SMRiP81929.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP81929.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEF1_PEA
AccessioniPrimary (citable) accession number: P81929
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: November 2, 2016
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.