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P81928

- 140U_DROME

UniProt

P81928 - 140U_DROME

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Protein

RPII140-upstream gene protein

Gene

140up

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Essential for viability.1 Publication

GO - Biological processi

  1. multicellular organismal development Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
RPII140-upstream gene protein
Gene namesi
Name:140up
ORF Names:CG9852
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0010340. 140up.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261RPII140-upstream gene proteinPRO_0000064352Add
BLAST

Proteomic databases

PaxDbiP81928.

Expressioni

Gene expression databases

BgeeiP81928.

Interactioni

Protein-protein interaction databases

BioGridi66797. 1 interaction.
STRINGi7227.FBpp0082370.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei67 – 8721HelicalSequence AnalysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence AnalysisAdd
BLAST
Transmembranei183 – 20321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG313919.
GeneTreeiENSGT00390000013817.
InParanoidiP81928.
OMAiNQATAFK.
OrthoDBiEOG7ZD1WV.
PhylomeDBiP81928.

Family and domain databases

InterProiIPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P81928-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNFLWKGRRF LIAGILPTFE GAADEIVDKE NKTYKAFLAS KPPEETGLER
60 70 80 90 100
LKQMFTIDEF GSISSELNSV YQAGFLGFLI GAIYGGVTQS RVAYMNFMEN
110 120 130 140 150
NQATAFKSHF DAKKKLQDQF TVNFAKGGFK WGWRVGLFTT SYFGIITCMS
160 170 180 190 200
VYRGKSSIYE YLAAGSITGS LYKVSLGLRG MAAGGIIGGF LGGVAGVTSL
210 220 230 240 250
LLMKASGTSM EEVRYWQYKW RLDRDENIQQ AFKKLTEDEN PELFKAHDEK
260
TSEHVSLDTI K
Length:261
Mass (Da):29,182
Last modified:March 28, 2003 - v2
Checksum:i5DB78CF6CFC4435A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti64 – 641S → F in AAD40352. (PubMed:1905256)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M62975 Genomic DNA. Translation: AAD40352.2.
AE014297 Genomic DNA. Translation: AAF55023.1.
AY058577 mRNA. Translation: AAL13806.1.
PIRiJQ1024.
RefSeqiNP_001262561.1. NM_001275632.1.
NP_476951.1. NM_057603.6.
UniGeneiDm.10056.

Genome annotation databases

EnsemblMetazoaiFBtr0082909; FBpp0082370; FBgn0010340.
GeneIDi41720.
KEGGidme:Dmel_CG9852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M62975 Genomic DNA. Translation: AAD40352.2 .
AE014297 Genomic DNA. Translation: AAF55023.1 .
AY058577 mRNA. Translation: AAL13806.1 .
PIRi JQ1024.
RefSeqi NP_001262561.1. NM_001275632.1.
NP_476951.1. NM_057603.6.
UniGenei Dm.10056.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 66797. 1 interaction.
STRINGi 7227.FBpp0082370.

Proteomic databases

PaxDbi P81928.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0082909 ; FBpp0082370 ; FBgn0010340 .
GeneIDi 41720.
KEGGi dme:Dmel_CG9852.

Organism-specific databases

CTDi 41720.
FlyBasei FBgn0010340. 140up.

Phylogenomic databases

eggNOGi NOG313919.
GeneTreei ENSGT00390000013817.
InParanoidi P81928.
OMAi NQATAFK.
OrthoDBi EOG7ZD1WV.
PhylomeDBi P81928.

Miscellaneous databases

GenomeRNAii 41720.
NextBioi 825226.
PROi P81928.

Gene expression databases

Bgeei P81928.

Family and domain databases

InterProi IPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view ]
Pfami PF02466. Tim17. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the promoter region of the housekeeping gene DmRP140 by sequence comparison of Drosophila melanogaster and Drosophila virilis."
    Sitzler S., Oldenburg I., Petersen G., Bautz E.K.F.
    Gene 100:155-162(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
    Tissue: Embryo.
  2. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  3. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
    Tissue: Embryo.

Entry informationi

Entry namei140U_DROME
AccessioniPrimary (citable) accession number: P81928
Secondary accession number(s): Q9VFM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 28, 2003
Last modified: October 1, 2014
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase

External Data

Dasty 3