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P81827

- UP1_RAT

UniProt

P81827 - UP1_RAT

Protein

Urinary protein 1

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Urinary protein 1
    Short name:
    UP-1
    Short name:
    rUP-1
    Alternative name(s):
    Liver regeneration-related protein LRRG05
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 8

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 21212 PublicationsAdd
    BLAST
    Chaini22 – 10180Urinary protein 1PRO_0000036169Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi24 ↔ 51Sequence Analysis
    Disulfide bondi27 ↔ 36Sequence Analysis
    Disulfide bondi43 ↔ 70Sequence Analysis
    Glycosylationi67 – 671N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi73 ↔ 89Sequence Analysis
    Disulfide bondi90 ↔ 96Sequence Analysis

    Post-translational modificationi

    N-glycosylated.Curated

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PRIDEiP81827.

    Expressioni

    Gene expression databases

    GenevestigatoriP81827.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000050106.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 UPAR/Ly6 domain.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    GeneTreeiENSGT00700000105314.
    HOGENOMiHOG000082505.
    HOVERGENiHBG017754.
    InParanoidiP81827.
    OMAiGFANERN.
    OrthoDBiEOG7BKCXJ.
    PhylomeDBiP81827.
    TreeFamiTF337781.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P81827-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKPILLLPL GLSLLMSSLL ALQCFRCESL DSTGLCRVGR RICQTYPDEI    50
    CAWVVVTTRD GKFVYGNQSC AECIGTTVEH GSLIISTNCC SATPFCNMVH 100
    P 101
    Length:101
    Mass (Da):10,960
    Last modified:May 30, 2000 - v1
    Checksum:i03021BC9FFE75646
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF198441 mRNA. Translation: AAF15598.1.
    AY327506 mRNA. Translation: AAP97738.1.
    RefSeqiNP_001030122.2. NM_001034950.2.
    UniGeneiRn.144564.
    Rn.224549.

    Genome annotation databases

    EnsembliENSRNOT00000042860; ENSRNOP00000050106; ENSRNOG00000045799.
    GeneIDi619560.
    KEGGirno:619560.
    UCSCiRGD:1561250. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF198441 mRNA. Translation: AAF15598.1 .
    AY327506 mRNA. Translation: AAP97738.1 .
    RefSeqi NP_001030122.2. NM_001034950.2.
    UniGenei Rn.144564.
    Rn.224549.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000050106.

    Proteomic databases

    PRIDEi P81827.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000042860 ; ENSRNOP00000050106 ; ENSRNOG00000045799 .
    GeneIDi 619560.
    KEGGi rno:619560.
    UCSCi RGD:1561250. rat.

    Organism-specific databases

    CTDi 619560.

    Phylogenomic databases

    GeneTreei ENSGT00700000105314.
    HOGENOMi HOG000082505.
    HOVERGENi HBG017754.
    InParanoidi P81827.
    OMAi GFANERN.
    OrthoDBi EOG7BKCXJ.
    PhylomeDBi P81827.
    TreeFami TF337781.

    Miscellaneous databases

    NextBioi 714650.

    Gene expression databases

    Genevestigatori P81827.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The characterisation of novel secreted Ly-6 proteins from rat urine by the combined use of two-dimensional gel electrophoresis, microbore high performance liquid chromatography and expressed sequence tag data."
      Southan C., Cutler P., Birrell H., Connell J., Fantom K.G.M., Sims M., Shaikh N., Schneider K.
      Proteomics 2:187-196(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 22-47, IDENTIFICATION.
      Tissue: Urine.
    2. "Liver regeneration after PH."
      Xu C.S., Li W.Q., Li Y.C., Han H.P., Wang G.P., Chai L.Q., Yang K.J., Yan H.M., Chang C.F., Zhao L.F., Ma H., Wang L., Wang S.F., Shi J.B., Rahman S., Wang Q.N., Zhang J.B.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Liver.
    3. "Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison."
      Wait R., Gianazza E., Eberini I., Sironi L., Dunn M.J., Gemeiner M., Miller I.
      Electrophoresis 22:3043-3052(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 22-37 AND 42-62.

    Entry informationi

    Entry nameiUP1_RAT
    AccessioniPrimary (citable) accession number: P81827
    Secondary accession number(s): Q53ZD7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 30, 2000
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3