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P81827 (UP1_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Urinary protein 1

Short name=UP-1
Short name=rUP-1
Alternative name(s):
Liver regeneration-related protein LRRG05
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length101 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted.

Post-translational modification

N-glycosylated Probable.

Sequence similarities

Contains 1 UPAR/Ly6 domain.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Ref.1 Ref.3
Chain22 – 10180Urinary protein 1
PRO_0000036169

Amino acid modifications

Glycosylation671N-linked (GlcNAc...) Potential
Disulfide bond24 ↔ 51 Potential
Disulfide bond27 ↔ 36 Potential
Disulfide bond43 ↔ 70 Potential
Disulfide bond73 ↔ 89 Potential
Disulfide bond90 ↔ 96 Potential

Sequences

Sequence LengthMass (Da)Tools
P81827 [UniParc].

Last modified May 30, 2000. Version 1.
Checksum: 03021BC9FFE75646

FASTA10110,960
        10         20         30         40         50         60 
MGKPILLLPL GLSLLMSSLL ALQCFRCESL DSTGLCRVGR RICQTYPDEI CAWVVVTTRD 

        70         80         90        100 
GKFVYGNQSC AECIGTTVEH GSLIISTNCC SATPFCNMVH P 

« Hide

References

« Hide 'large scale' references
[1]"The characterisation of novel secreted Ly-6 proteins from rat urine by the combined use of two-dimensional gel electrophoresis, microbore high performance liquid chromatography and expressed sequence tag data."
Southan C., Cutler P., Birrell H., Connell J., Fantom K.G.M., Sims M., Shaikh N., Schneider K.
Proteomics 2:187-196(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 22-47, IDENTIFICATION.
Tissue: Urine.
[2]"Liver regeneration after PH."
Xu C.S., Li W.Q., Li Y.C., Han H.P., Wang G.P., Chai L.Q., Yang K.J., Yan H.M., Chang C.F., Zhao L.F., Ma H., Wang L., Wang S.F., Shi J.B., Rahman S., Wang Q.N., Zhang J.B.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Liver.
[3]"Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison."
Wait R., Gianazza E., Eberini I., Sironi L., Dunn M.J., Gemeiner M., Miller I.
Electrophoresis 22:3043-3052(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 22-37 AND 42-62.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF198441 mRNA. Translation: AAF15598.1.
AY327506 mRNA. Translation: AAP97738.1.
RefSeqNP_001030122.2. NM_001034950.2.
UniGeneRn.144564.
Rn.224549.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000050106.

Proteomic databases

PRIDEP81827.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000042860; ENSRNOP00000050106; ENSRNOG00000045799.
GeneID619560.
KEGGrno:619560.
UCSCRGD:1561250. rat.

Organism-specific databases

CTD619560.

Phylogenomic databases

GeneTreeENSGT00700000105314.
HOGENOMHOG000082505.
HOVERGENHBG017754.
InParanoidP81827.
OrthoDBEOG7BKCXJ.
PhylomeDBP81827.
TreeFamTF337781.

Gene expression databases

GenevestigatorP81827.

Family and domain databases

ProtoNetSearch...

Other

NextBio714650.

Entry information

Entry nameUP1_RAT
AccessionPrimary (citable) accession number: P81827
Secondary accession number(s): Q53ZD7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families