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P81800

- PPB1_PREIN

UniProt

P81800 - PPB1_PREIN

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Protein

Alkaline phosphatase

Gene
N/A
Organism
Prevotella intermedia
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Acts against tyrosine-phosphatases.Curated

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Enzyme regulationi

Completely inhibited by thiol-reducing agents, such as DTT and 2-mercaptoethanol. Activity was also inhibited by sodium orthovanadate, sodium molybdate, N-ethylmaleimide, EDTA and zinc ion, but was not inhibited by okadaic acid.

GO - Molecular functioni

  1. alkaline phosphatase activity Source: UniProtKB

GO - Biological processi

  1. dephosphorylation Source: GOC
  2. metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphatase (EC:3.1.3.1)
Short name:
ALPase
Alternative name(s):
PiALP
OrganismiPrevotella intermediaCurated
Taxonomic identifieri28131 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›20›20Alkaline phosphatasePRO_0000058533Add
BLAST

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodimer; may be disulfide-linked.Curated

Sequencei

Sequence statusi: Fragment.

P81800-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20
TDMLAVSVSS TDAIGHKYGT
Length:20
Mass (Da):2,053
Last modified:June 1, 2001 - v1
Checksum:iA8D8A9276AE0ED83
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Curated
Non-terminal residuei20 – 201Curated

Cross-referencesi

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia."
    Ansai T., Awano S., Chen X., Fuchi T., Arimoto T., Akifusa S., Takehara T.
    FEBS Lett. 428:157-160(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, CHARACTERIZATION.
    Strain: ATCC 25611 / DSM 20706 / JCM 12248 / NCTC 13070 / VPI 4197.

Entry informationi

Entry nameiPPB1_PREIN
AccessioniPrimary (citable) accession number: P81800
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: October 1, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

External Data

Dasty 3