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P81800

- PPB1_PREIN

UniProt

P81800 - PPB1_PREIN

Protein

Alkaline phosphatase

Gene
N/A
Organism
Prevotella intermedia
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Acts against tyrosine-phosphatases.Curated

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Enzyme regulationi

    Completely inhibited by thiol-reducing agents, such as DTT and 2-mercaptoethanol. Activity was also inhibited by sodium orthovanadate, sodium molybdate, N-ethylmaleimide, EDTA and zinc ion, but was not inhibited by okadaic acid.

    GO - Molecular functioni

    1. alkaline phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. dephosphorylation Source: GOC
    2. metabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alkaline phosphatase (EC:3.1.3.1)
    Short name:
    ALPase
    Alternative name(s):
    PiALP
    OrganismiPrevotella intermediaCurated
    Taxonomic identifieri28131 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›20›20Alkaline phosphatasePRO_0000058533Add
    BLAST

    Post-translational modificationi

    The N-terminus is blocked.

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Subunit structurei

    Homodimer; may be disulfide-linked.Curated

    Sequencei

    Sequence statusi: Fragment.

    P81800-1 [UniParc]FASTAAdd to Basket

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    TDMLAVSVSS TDAIGHKYGT                                    20
    Length:20
    Mass (Da):2,053
    Last modified:June 1, 2001 - v1
    Checksum:iA8D8A9276AE0ED83
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Curated
    Non-terminal residuei20 – 201Curated

    Cross-referencesi

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia."
      Ansai T., Awano S., Chen X., Fuchi T., Arimoto T., Akifusa S., Takehara T.
      FEBS Lett. 428:157-160(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE, CHARACTERIZATION.
      Strain: ATCC 25611 / DSM 20706 / JCM 12248 / NCTC 13070 / VPI 4197.

    Entry informationi

    Entry nameiPPB1_PREIN
    AccessioniPrimary (citable) accession number: P81800
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 10, 2004
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    External Data

    Dasty 3