Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alkaline phosphatase

Gene
N/A
Organism
Prevotella intermedia
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Acts against tyrosine-phosphatases.Curated

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Enzyme regulationi

Completely inhibited by thiol-reducing agents, such as DTT and 2-mercaptoethanol. Activity was also inhibited by sodium orthovanadate, sodium molybdate, N-ethylmaleimide, EDTA and zinc ion, but was not inhibited by okadaic acid.

GO - Molecular functioni

  • alkaline phosphatase activity Source: UniProtKB

GO - Biological processi

  • metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphatase (EC:3.1.3.1)
Short name:
ALPase
Alternative name(s):
PiALP
OrganismiPrevotella intermediaCurated
Taxonomic identifieri28131 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000058533‹1 – ›20Alkaline phosphataseAdd BLAST›20

Post-translational modificationi

The N-terminus is blocked.

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodimer; may be disulfide-linked.Curated

Sequencei

Sequence statusi: Fragment.

P81800-1 [UniParc]FASTAAdd to basket

« Hide

        10         20
TDMLAVSVSS TDAIGHKYGT
Length:20
Mass (Da):2,053
Last modified:June 1, 2001 - v1
Checksum:iA8D8A9276AE0ED83
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Curated1
Non-terminal residuei20Curated1

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiPPB1_PREIN
AccessioniPrimary (citable) accession number: P81800
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: July 6, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.