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Reviewed, UniProtKB/Swiss-Prot P81764 (ADHR_DROPS)

Last modified June 16, 2009. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Alcohol dehydrogenase-related 31 kDa protein
Gene names
Name: Adhr
Synonyms: Adh-dup
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly) [Complete proteome]
Taxonomic identifier46245 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionalcohol dehydrogenase activity

Inferred from electronic annotation. Source: InterPro

binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Alcohol dehydrogenase-related 31 kDa protein
PRO_0000054511

Regions

Nucleotide binding11 – 3424NAD or NADP By similarity

Sites

Active site1521Proton acceptor By similarity
Binding site1391Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
P81764-1 [UniParc].

Last modified May 30, 2000. Version 1.
Checksum: 6FDE371F3D1AF774

FASTA27830,895
        10         20         30         40         50         60 
MYDLTGKHVC YVADCGGIAL ETSKVLMTKN IAKLAILQSV ENPPAIAQLQ SIKHSTQIFF 

        70         80         90        100        110        120 
WTFDVTMARE EMKKYFDEVM VQMDYIDVLI NGATLCDERN IDATINTNLT GMMNTVATVL 

       130        140        150        160        170        180 
PYMDRKMGGS GGLIVNVTSV IGLDPSPVFC AYSASKFGVI GFTRSLADPL YYTQNGVAVM 

       190        200        210        220        230        240 
AVCCGPTKVF VDRELTAFLE YGQSFADRLR RAPCQSTAVC GQNIVNAIER SENGQIWIAD 

       250        260        270 
KGGLESVALH WYWHMADQFV NYMQSTDDED QEFFLGQR 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of the Adh gene region of Drosophila pseudoobscura: evolutionary change and evidence for an ancient gene duplication."
Schaeffer S.W., Aquadro C.F.
Genetics 117:61-73(1987) [PubMed: 3666441] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Molecular population genetics of sequence length diversity in the Adh region of Drosophila pseudoobscura."
Schaeffer S.W.
Genet. Res. 80:163-175(2002) [PubMed: 12688655] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: PS271.
[3]"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. expand/collapse author list , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
Genome Res. 15:1-18(2005) [PubMed: 15632085] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MV2-25.

Cross-references

Sequence databases

Y00602 Genomic DNA. Translation: CAA68646.1.
U64535 Genomic DNA. Translation: AAL35977.1.
CH379058 Genomic DNA. No translation available.
PIRS07246.

3D structure databases

HSSPHSSP built from PDB template 1B16 based on UniProtKB P10807.
ModBaseSearch...

Organism-specific databases

FlyBaseFBgn0012689. Dpse\Adhr.

Family and domain databases

InterProIPR002427. ADH-rel.
IPR002198. DH_sc/Rdtase_SDR.
IPR002424. Insect_AlcDH_fam.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR19410. ADH_short_C2. 1 hit.
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR01170. ADHRELATED.
PR01167. INSADHFAMILY.
PR00080. SDRFAMILY.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADHR_DROPS
AccessionPrimary (citable) accession number: P81764
Secondary accession number(s): P26621, Q53WW1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: June 16, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectDrosophila annotation project

Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents