P81764 (ADHR_DROPS) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 54.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Alcohol dehydrogenase-related 31 kDa protein | ||||||
| Gene names |
| ||||||
| Organism | Drosophila pseudoobscura pseudoobscura (Fruit fly) | ||||||
| Taxonomic identifier | 46245 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora |
Protein attributes
| Sequence length | 278 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Molecular function | alcohol dehydrogenase (NAD) activity Inferred from electronic annotation. Source: InterPro nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 278 | 278 | Alcohol dehydrogenase-related 31 kDa protein | PRO_0000054511 | |||||
Regions | |||||||||
| Nucleotide binding | 11 – 34 | 24 | NAD or NADP By similarity | ||||||
Sites | |||||||||
| Active site | 152 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 139 | 1 | Substrate By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 172 | 1 | F → Y in CAA68646. Ref.1 | ||||||
| Sequence conflict | 172 | 1 | F → Y in AAL35977. Ref.2 | ||||||
| Sequence conflict | 200 | 1 | A → E in CAA68646. Ref.1 | ||||||
| Sequence conflict | 200 | 1 | A → E in AAL35977. Ref.2 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Nucleotide sequence of the Adh gene region of Drosophila pseudoobscura: evolutionary change and evidence for an ancient gene duplication." Schaeffer S.W., Aquadro C.F. Genetics 117:61-73(1987) [PubMed: 3666441] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Molecular population genetics of sequence length diversity in the Adh region of Drosophila pseudoobscura." Schaeffer S.W. Genet. Res. 80:163-175(2002) [PubMed: 12688655] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PS271. |
| [3] | "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. Gibbs R.A.Genome Res. 15:1-18(2005) [PubMed: 15632085] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | Y00602 Genomic DNA. Translation: CAA68646.1. U64535 Genomic DNA. Translation: AAL35977.1. CH379058 Genomic DNA. Translation: EDY69784.1. |
| PIR | S07246. |
| RefSeq | XP_002132382.1. XM_002132346.1. |
3D structure databases | |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 6903503. |
| KEGG | dpo:Dpse_GA25223. |
Organism-specific databases | |
| FlyBase | FBgn0012689. Dpse\Adhr. |
Phylogenomic databases | |
| InParanoid | P81764. |
| OrthoDB | EOG44F4RW. |
Family and domain databases | |
| InterPro | IPR002427. ADH-rel. IPR002424. ADH_insect. IPR002198. DH_sc/Rdtase_SDR. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| Pfam | PF00106. adh_short. 1 hit. [Graphical view] |
| PRINTS | PR01170. ADHRELATED. PR01167. INSADHFAMILY. PR00080. SDRFAMILY. |
| PROSITE | PS00061. ADH_SHORT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ADHR_DROPS | ||||||||
| Accession | Primary (citable) accession number: P81764 Secondary accession number(s): B5DHK7, P26621, Q53WW1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Drosophila annotation project | ||||||||
Relevant documents
| Drosophila Drosophila: entries, gene names and cross-references to FlyBase |
| SIMILARITY comments Index of protein domains and families |

Clusters with