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Protein

Aminopeptidase N

Gene
N/A
Organism
Helicoverpa armigera (Cotton bollworm) (Heliothis armigera)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Acts as a receptor for B.thuringiensis Cry1Ac delta-endotoxin.1 Publication

Catalytic activityi

Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.1 Publication

Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Enzyme regulationi

Inhibited by the zinc-chelators 2,2-dipyridyl and 1,10-phenanthroline.1 Publication

GO - Molecular functioni

Keywordsi

Molecular functionAminopeptidase, Hydrolase, Metalloprotease, Protease
LigandZinc

Names & Taxonomyi

Protein namesi
Recommended name:
Aminopeptidase N (EC:3.4.11.2)
Short name:
AP-N
Alternative name(s):
CryIA(C) receptor
OrganismiHelicoverpa armigera (Cotton bollworm) (Heliothis armigera)
Taxonomic identifieri29058 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaNoctuoideaNoctuidaeHeliothinaeHelicoverpa

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000950861 – ›10Aminopeptidase N›10

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M1 family.Curated

Sequencei

Sequence statusi: Fragment.

Length:10
Mass (Da):1,093
Last modified:May 30, 2000 - v1
Checksum:i05042EB87B11F1BB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei101

Entry informationi

Entry nameiAMPN_HELAM
AccessioniPrimary (citable) accession number: P81731
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: April 12, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families