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P81657 (VA5_VESMA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Venom allergen 5
Alternative name(s):
Antigen 5
Short name=Ag5
Cysteine-rich venom protein
Short name=CRVP
Allergen=Vesp m 5
OrganismVespa mandarinia (Asian giant hornet)
Taxonomic identifier7446 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaVespidaeVespinaeVespa

Protein attributes

Sequence length202 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted.

Tissue specificity

Expressed by the venom gland.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the CRISP family.

Contains 1 SCP domain.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   PTMDisulfide bond
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 202202Venom allergen 5
PRO_0000211543

Regions

Domain46 – 187142SCP

Amino acid modifications

Disulfide bond4 ↔ 16 By similarity
Disulfide bond8 ↔ 101 By similarity
Disulfide bond26 ↔ 94 By similarity
Disulfide bond168 ↔ 185 By similarity

Sequences

Sequence LengthMass (Da)Tools
P81657 [UniParc].

Last modified July 15, 1999. Version 1.
Checksum: 686351357B01F4EF

FASTA20222,547
        10         20         30         40         50         60 
NNYCKIKCRS GIHTLCKFGI STKPNCGKNV VKASGLTKAE KLEILKQHNE FRQKVARGLE 

        70         80         90        100        110        120 
TRGKPGPQPP AKSMNTLVWN DELAQIAQVW AGQCDYGHDV CRNTAKYSVG QNIAENGSTA 

       130        140        150        160        170        180 
ASFASVSNMV QMWADEVKNY QYGSTKNKLI EVGHYTQMVW AKTKEIGCGS IKYIENGWHR 

       190        200 
HYLVCNYGPA GNIGNEPIYE RK 

« Hide

References

[1]Hoffman D.R., Schmidt J.O.
Submitted (FEB-1998) to UniProtKB
Cited for: PROTEIN SEQUENCE.
Tissue: Venom.

Cross-references

3D structure databases

ProteinModelPortalP81657.
SMRP81657. Positions 1-202.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome3526. Vesp m 5.0101.
678. Vesp m 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.33.10. 1 hit.
InterProIPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
IPR002413. V5_allergen.
[Graphical view]
PANTHERPTHR10334. PTHR10334. 1 hit.
PfamPF00188. CAP. 1 hit.
[Graphical view]
PRINTSPR00838. V5ALLERGEN.
PR00837. V5TPXLIKE.
SMARTSM00198. SCP. 1 hit.
[Graphical view]
SUPFAMSSF55797. SSF55797. 1 hit.
PROSITEPS01009. CRISP_1. 1 hit.
PS01010. CRISP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVA5_VESMA
AccessionPrimary (citable) accession number: P81657
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: July 15, 1999
Last modified: October 16, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries