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P81656

- VA5_POLDO

UniProt

P81656 - VA5_POLDO

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Protein
Venom allergen 5
Gene
N/A
Organism
Polistes dominula (European paper wasp) (Vespa dominula)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Venom allergen 5
Alternative name(s):
Antigen 5
Short name:
Ag5
Cysteine-rich venom protein
Short name:
CRVP
Allergen: Pol d 5
OrganismiPolistes dominula (European paper wasp) (Vespa dominula)
Taxonomic identifieri743375 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaVespidaePolistinaePolistiniPolistes

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3438. Pol d 5.0101.
588. Pol d 5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed prediction
Add
BLAST
Chaini22 – 227206Venom allergen 5
PRO_0000211534Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi25 ↔ 37 By similarity
Disulfide bondi29 ↔ 125 By similarity
Disulfide bondi49 ↔ 117 By similarity
Disulfide bondi193 ↔ 210 By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Structurei

3D structure databases

ProteinModelPortaliP81656.
SMRiP81656. Positions 19-227.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini69 – 212144SCP
Add
BLAST

Sequence similaritiesi

Belongs to the CRISP family.
Contains 1 SCP domain.

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.40.33.10. 1 hit.
InterProiIPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
IPR002413. V5_allergen.
[Graphical view]
PANTHERiPTHR10334. PTHR10334. 1 hit.
PfamiPF00188. CAP. 1 hit.
[Graphical view]
PRINTSiPR00838. V5ALLERGEN.
PR00837. V5TPXLIKE.
SMARTiSM00198. SCP. 1 hit.
[Graphical view]
SUPFAMiSSF55797. SSF55797. 1 hit.
PROSITEiPS01009. CRISP_1. 1 hit.
PS01010. CRISP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P81656-1 [UniParc]FASTAAdd to Basket

« Hide

MKISCLICLV IVLTIIHLSQ ANDYCKIKCS SGVHTVCQYG ESTKPSKNCA    50
GKLIKSVGPT EEEKKLIVEE HNRFRQKVAK GLETRGNPGP QPAASNMNNL 100
VWNDELAKIA QVWASQCQIL VHDKCRNTEK YQVGQNIAYA GSSNHFPSVT 150
KLIQLWENEV KDFNYNTGIT NKNFGKVGHY TQMVWGNTKE VGCGSLKYVE 200
KNMQIHYLIC NYGPAGNYLG QPIYTKK 227
Length:227
Mass (Da):25,446
Last modified:November 30, 2010 - v2
Checksum:iF9FD14065F3E529B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY685000 mRNA. Translation: AAT95010.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY685000 mRNA. Translation: AAT95010.1 .

3D structure databases

ProteinModelPortali P81656.
SMRi P81656. Positions 19-227.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 3438. Pol d 5.0101.
588. Pol d 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.33.10. 1 hit.
InterProi IPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
IPR002413. V5_allergen.
[Graphical view ]
PANTHERi PTHR10334. PTHR10334. 1 hit.
Pfami PF00188. CAP. 1 hit.
[Graphical view ]
PRINTSi PR00838. V5ALLERGEN.
PR00837. V5TPXLIKE.
SMARTi SM00198. SCP. 1 hit.
[Graphical view ]
SUPFAMi SSF55797. SSF55797. 1 hit.
PROSITEi PS01009. CRISP_1. 1 hit.
PS01010. CRISP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequences of paper wasp venom antigen 5."
    Morris P.R., Schmidt M., Hoffman D.R.
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Venom gland.
  2. Hoffman D.R.
    Submitted (FEB-1999) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 22-227.
    Tissue: Venom.

Entry informationi

Entry nameiVA5_POLDO
AccessioniPrimary (citable) accession number: P81656
Secondary accession number(s): Q68KJ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 30, 2010
Last modified: December 11, 2013
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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