P81651 (NLTP1_PRUAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Non-specific lipid-transfer protein 1 Short name=LTP 1 Alternative name(s): Major allergen Pru ar 3 Allergen=Pur ar 3
Organism	Prunus armeniaca (Apricot)
Taxonomic identifier	36596 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Rosales › Rosaceae › Maloideae › Amygdaleae › Prunus

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the plant LTP family.

Ontologies

Keywords
Biological process	Transport
Disease	Allergen
Ligand	Lipid-binding
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	lipid transport Inferred from electronic annotation. Source: InterPro
Molecular function	lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Non-specific lipid-transfer protein 1		PRO_0000153877
Amino acid modifications
	Disulfide bond	3 ↔ 50		By similarity
	Disulfide bond	13 ↔ 27		By similarity
	Disulfide bond	28 ↔ 73		By similarity
	Disulfide bond	48 ↔ 87		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P81651 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: 98A91F6B30CD8435	FASTA	91	9,179
	10 20 30 40 50 60 ITCGQVSSSL APCIGYVRGG GAVPPACCNG IRNVNNLART TPDRRTACNC LKQLSGSISG 70 80 90 VNPNNAAALP GKCGVNIPYK ISASTNCATV K

References

[1]	"Determination of the primary structure of two lipid transfer proteins from apricot (Prunus armeniaca)." Conti A., Fortunato D., Ortolani C., Giuffrida M.G., Pravettoni V., Napolitano L., Farioli L., Perono Garoffo L., Trambaioli C., Pastorello E.A. J. Chromatogr. B 756:123-129(2001) [PubMed: 11419703] [Abstract] Cited for: PROTEIN SEQUENCE.
[2]	"The major allergen of apricot (Prunus armeniaca) is a lipid transfer protein." Conti A., Baroglio C., Monza M., Ortolani C., Scibola E., Giuffrida M.G., Fortunato D., Farioli L., Pravettoni V., Ansaloni R., Napolitano L., Pastorello E.A. Submitted (JAN-1999) to UniProtKB Cited for: PROTEIN SEQUENCE OF 1-34.
+	Additional computationally mapped references.

Cross-references

3D structure databases
ProteinModelPortal	P81651.
SMR	P81651. Positions 1-91.
ModBase	Search...
Protein family/group databases
Allergome	3447. Pru ar 3.0101. 596. Pru ar 3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR016140. Bifunc_inhib/LTP/seed_store. IPR013770. Lipid_transfer_prot_hlx-dom. IPR003612. LTP/seed_store/tryp_amyl_inhib. IPR000528. Plant_LTP. [Graphical view]
Gene3D	G3DSA:1.10.110.10. LPT_helical. 1 hit.
Pfam	PF00234. Tryp_alpha_amyl. 1 hit. [Graphical view]
PRINTS	PR00382. LIPIDTRNSFER.
SMART	SM00499. AAI. 1 hit. [Graphical view]
SUPFAM	SSF47699. Bifunc_inhib/LTP/seed_store. 1 hit.
PROSITE	PS00597. PLANT_LTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NLTP1_PRUAR

Accession

Primary (citable) accession number: P81651

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	May 30, 2000
Last modified:	October 19, 2011
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program