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Protein

Pollen allergen Ole e 7

Gene
N/A
Organism
Olea europaea (Common olive)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Pollen allergen Ole e 7
Alternative name(s):
Allergen Ole e VII
Allergen: Ole e 7
OrganismiOlea europaea (Common olive)
Taxonomic identifieri4146 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesOleaceaeOleeaeOlea

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Allergen from olive pollen. Important in Mediterranean countries and California. Its prevalence is related to the geographic area.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3388. Ole e 7.0101.
495. Ole e 7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›21›21Pollen allergen Ole e 7PRO_0000064563Add
BLAST

Sequencei

Sequence statusi: Fragment.

P81430-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
APSQSTVTAL LTSCVSYIDD Q
Length:21
Mass (Da):2,199
Last modified:July 26, 2002 - v2
Checksum:iF0E9B99FEB079400
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei21 – 211

Polymorphismi

Many isoforms of the allergen exist due to polymorphism. They can be classified as isoforms of type A (shown here) and isoforms of type B. A microheterogeneity is detected at positions 4 and 11 of isoforms of type A and at positions 4, 5, 10 and 11 of isoforms of type B.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti5 – 51S → G in type B.
Natural varianti10 – 101L → K in type B.
Natural varianti18 – 181I → K in type B.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3388. Ole e 7.0101.
495. Ole e 7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Identification, isolation, and characterization of Ole e 7, a new allergen of olive tree pollen."
    Tejera M.L., Villalba M., Batanero E., Rodriguez R.
    J. Allergy Clin. Immunol. 104:797-802(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE (VARIANTS A AND B), IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Pollen.
  2. "An allergen from Olea europaea pollen (Ole e 7) is associated with plant-derived food anaphylaxis."
    Florido Lopez J.F., Quiralte Enriquez J., Arias de Saavedra Alias J.M., Saenz de San Pedro B., Martin Casanez E.
    Allergy 57:53-59(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: ALLERGEN.
  3. "Profiling of hydrophilic proteins from Olea europaea olive pollen by MALDI TOF mass spectrometry."
    Napoli A., Aiello D., Di Donna L., Sajjad A., Perri E., Sindona G.
    Anal. Chem. 78:3434-3443(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, VARIANTS.
  4. Cited for: REVIEW, NOMENCLATURE.

Entry informationi

Entry nameiALL7_OLEEU
AccessioniPrimary (citable) accession number: P81430
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: July 26, 2002
Last modified: October 1, 2014
This is version 31 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.