Reviewed, UniProtKB/Swiss-Prot P81422 (CATA_ACIRA)

Names and origin

Protein names	Recommended name:     Catechol 1,2-dioxygenase     EC=1.13.11.1 Alternative name(s):     1,2-CTD
Organism	Acinetobacter radioresistens
Taxonomic identifier	40216 [NCBI]
Taxonomic lineage	Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Catechol + O(2) = cis,cis-muconate.
Cofactor	Binds 1 Fe(3+) ion per subunit.
Pathway	Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-4,5-dihydrofuran-2-acetate from catechol: step 1/3.
Subunit structure	Homodimer which dissociates into active monomeric subunits at high ionic strengths.
Sequence similarities	Belongs to the intradiol ring-cleavage dioxygenase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Ligand	Iron
Molecular function	Dioxygenase Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catechol 1,2-dioxygenase activity Inferred from electronic annotation. Source: EC iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›20	›20	Catechol 1,2-dioxygenase		PRO_0000085083
Experimental info
	Non-terminal residue	20	1

Sequences

	Sequence		Length	Mass (Da)
	P81422-1 [UniParc]. Last modified December 15, 1998. Version 1. Checksum: 70E8A5038F802327	FASTA	20	2,279
	10 20 TAANVKIFNT EEVQNFINLL

References

[1]	"Purification, biochemical properties and substrate specificity of a catechol 1,2-dioxygenase from a phenol degrading Acinetobacter radioresistens." Briganti F., Pessione E., Giunta C., Scozzafava A. FEBS Lett. 416:61-64(1997) [PubMed: 9369233] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR000627. Intradiol_dOase_C. [Graphical view]
PROSITE	PS00083. INTRADIOL_DIOXYGENAS. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_ACIRA

Accession

Primary (citable) accession number: P81422

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	December 15, 1998
Last modified:	November 4, 2008
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)