P81332 (ACDE_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetyl-CoA decarbonylase/synthase complex subunit epsilon
Short name=ACDS complex subunit epsilon

Gene names

Name:	cdhB
Ordered Locus Names:	MJ0154

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO2. Probably has a structural role in stabilizing the alpha-epsilon subcomponent of the ACDS complex by forming a structural link between the two alpha subunits By similarity. HAMAP MF_01134
Subunit structure	Heterotetramer of two alpha and two epsilon chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha2epsilon2)(4)-beta(8)-(gamma1delta1)8 Potential.
Sequence similarities	Belongs to the CdhB family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	methanogenesis, from acetate Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 146	146	Acetyl-CoA decarbonylase/synthase complex subunit epsilon HAMAP MF_01134		PRO_0000155090

Sequences

	Sequence		Length	Mass (Da)
	P81332 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: EFF8B65DDF4518D6	FASTA	146	16,858
	10 20 30 40 50 60 MDERFIAYIP TAGSNVAHAE ITSPTLVKMM IRRAKKPILI LGENLEENEK ELISKLIEKF 70 80 90 100 110 120 NLKTIKTPEE MNLMAIMKYL ASSDYDLALF TGITYYYLAQ AATHLKQFSN VVTISIDKYY 130 140 QPNTLYSFPN LSKEEYLDYL RKLLEG

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98136.1.
RefSeq	NP_247122.1. NC_000909.1.
3D structure databases
ProteinModelPortal	P81332.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1450998.
GenomeReviews	Gene locus MJ0154 in contig L77117_GR.
KEGG	mja:MJ_0154.
NMPDR	fig|243232.1.peg.159.
TIGR	MJ0154.
Phylogenomic databases
HOGENOM	HBG540974.
OMA	ITYYYLA.
ProtClustDB	PRK00945.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0154-MONOMER.
Family and domain databases
HAMAP	MF_01134. CdhB. [Tree]
InterPro	IPR003704. CO_DH_CoA_synth. [Graphical view]
KO	K00195.
Pfam	PF02552. CO_dh. 1 hit. [Graphical view]
PIRSF	PIRSF006035. CO_dh_b_ACDS_e. 1 hit.
TIGRFAMs	TIGR00315. CdhB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ACDE_METJA

Accession

Primary (citable) accession number: P81332

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 21, 2003
Last sequence update:	June 1, 1998
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program