Reviewed,
UniProtKB/Swiss-Prot P81246 (PDIA3_PAPHA)
Last modified
January 19, 2010.
Version 57.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Protein disulfide-isomerase A3 EC=5.3.4.1 Alternative name(s): 58 kDa microsomal protein ER58 | ||||
| Gene names |
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| Organism | Papio hamadryas (Hamadryas baboon) | ||||
| Taxonomic identifier | 9557 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Papio |
Protein attributes
| Sequence length | 39 AA. |
| Sequence status | Fragments. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | Catalyzes the rearrangement of -S-S- bonds in proteins. |
| Subunit structure | Interacts with ERP27 and CANX By similarity. |
| Subcellular location | Endoplasmic reticulum lumen. Melanosome By similarity. |
| Tissue specificity | Predominantly expressed in liver. Low in brain, testis and colon. Not detectable in pancreas and skeletal muscle. |
| Sequence similarities | Belongs to the protein disulfide isomerase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Endoplasmic reticulum |
| Domain | Redox-active center |
| Molecular function | Isomerase |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Cellular component | endoplasmic reticulum lumen Inferred from electronic annotation. Source: UniProtKB-SubCell melanosomeInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein disulfide isomerase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "Purification of a 58-kDa protein (ER58) from monkey liver microsomes and comparison with protein-disulfide isomerase." Bonfils C. Eur. J. Biochem. 254:420-427(1998) [PubMed: 9660200] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Hepatocyte. |
Cross-references
Entry information
| Entry name | PDIA3_PAPHA | ||||||||
| Accession | Primary (citable) accession number: P81246 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||

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