P81225 (CU21_LOCMI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cuticle protein 21

Alternative name(s):
LM-ACP 21

Gene names

Name:

ACP21

Organism

Locusta migratoria (Migratory locust)

Taxonomic identifier

7004 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Sequence similarities	Contains 1 chitin-binding type R&R domain.

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Cuticle protein 21		PRO_0000196101
Regions
	Repeat	21 – 24	4	1
	Repeat	27 – 30	4	2
	Repeat	33 – 36	4	3
	Repeat	39 – 42	4	4
	Repeat	47 – 50	4	5
	Repeat	53 – 56	4	6
	Domain	65 – 135	71	Chitin-binding type R&R
	Repeat	140 – 143	4	7
	Repeat	146 – 149	4	8
	Repeat	160 – 163	4	9

Sequences

	Sequence		Length	Mass (Da)
	P81225 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: 529144B53A131BDE	FASTA	169	16,879
	10 20 30 40 50 60 GYLGAPAVYA PGAPIAARAY AAPVAYAAPA LRAAPVAYAA PAVAKVAAPV AYAAPAAVAA 70 80 90 100 110 120 EYDPNPQYSY AYNVQDALTG DSKAQQETRD GDVVQGSYSL VEPDGSIRTV DYTADPVNGF 130 140 150 160 NAVVHKEAGA HPAPVVAKVA APVAYAAPAI AKVAAPLAYA APAYGKASH

References

[1]

"Primary structure of two major cuticular proteins from the migratory locust, Locusta migratoria, and their identification in polyacrylamide gels by mass spectrometry." Jensen C., Andersen S.O., Roepstorff P. Biochim. Biophys. Acta 1429:151-162(1998) [PubMed: 9920393] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Cuticle.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000618. Insect_cuticle. [Graphical view]
Pfam	PF00379. Chitin_bind_4. 1 hit. [Graphical view]
PRINTS	PR00947. CUTICLE.
PROSITE	PS00233. CHIT_BIND_RR_1. 1 hit. PS51155. CHIT_BIND_RR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CU21_LOCMI

Accession

Primary (citable) accession number: P81225
Secondary accession number(s): P81226

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)