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Protein

Dander allergen Equ c 2.0101

Gene
N/A
Organism
Equus caballus (Horse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Dander allergen Equ c 2.0101
Alternative name(s):
Allergen: Equ c 2.0101
OrganismiEquus caballus (Horse)
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
ProteomesiUP000002281 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Potent allergen of horse dander.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei332. Equ c 2.
333. Equ c 2.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›29›29Dander allergen Equ c 2.0101PRO_0000201032Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P81216-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
SQXPQSETDY SQLSGEWNTI YGAASNIXK
Length:29
Mass (Da):3,198
Last modified:July 15, 1998 - v1
Checksum:i4BBE0D9FF17A4EC6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei29 – 291

Mass spectrometryi

Molecular mass is 16000 Da from positions 1 - ?. Determined by ESI. 1 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei332. Equ c 2.
333. Equ c 2.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Separation of horse dander allergen proteins by two-dimensional electrophoresis -- molecular characterisation and identification of Equ c 2.0101 and Equ c 2.0102 as lipocalin proteins."
    Bulone V., Krogstad-Johnsen T., Smestad-Paulsen B.
    Eur. J. Biochem. 253:202-211(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, ALLERGEN.
    Tissue: Skin.
  2. "Biochemical characterization and surfactant properties of horse allergens."
    Goubran Botros H., Poncet P., Rabillon J., Fontaine T., Laval J.-M., David B.
    Eur. J. Biochem. 268:3126-3136(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: MASS SPECTROMETRY.
    Tissue: Dander.

Entry informationi

Entry nameiALL21_HORSE
AccessioniPrimary (citable) accession number: P81216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: January 7, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Caution

Equ c 2.0101 and c 2.0102 might be two variants of the same protein.Curated

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.