ID   GUN_SCHCO               Reviewed;          28 AA.
AC   P81190;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Endoglucanase;
DE            EC=3.2.1.4;
DE   AltName: Full=Cellulase;
DE   AltName: Full=Endo-1,4-beta-glucanase;
DE   Flags: Fragment;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=9315718; DOI=10.1016/s0014-5793(97)01049-1;
RA   Clarke A.J., Drummelsmith J., Yaguchi M.;
RT   "Identification of the catalytic nucleophile in the cellulase from
RT   Schizophyllum commune and assignment of the enzyme to family 5, subtype 5
RT   of the glycosidases.";
RL   FEBS Lett. 414:359-361(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P81190; -.
DR   SMR; P81190; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Cell membrane; Cellulose degradation;
KW   Direct protein sequencing; Glycosidase; Hydrolase; Lipoprotein; Membrane;
KW   Polysaccharide degradation; Zymogen.
FT   CHAIN           1..>28
FT                   /note="Endoglucanase"
FT                   /id="PRO_0000184053"
FT   ACT_SITE        20
FT                   /note="Nucleophile"
FT   NON_TER         28
SQ   SEQUENCE   28 AA;  2937 MW;  B3F1C0C99C9950BE CRC64;
     SLQAATEWLK ANNQRGFLGE MGAGSNAD
//