P81190 (GUN_SCHCO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Endoglucanase EC=3.2.1.4 Alternative name(s): Cellulase Endo-1,4-beta-glucanase
Organism	Schizophyllum commune (Split gill fungus)
Taxonomic identifier	5334 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Agaricomycetes › Agaricomycetidae › Agaricales › Schizophyllaceae › Schizophyllum

Protein attributes

Sequence length	28 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Subcellular location	Cell membrane; Lipid-anchor Probable.
Sequence similarities	Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cellulose degradation Polysaccharide degradation
Cellular component	Cell membrane Membrane
Molecular function	Glycosidase Hydrolase
PTM	Lipoprotein Zymogen
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cellulase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›28	›28	Endoglucanase		PRO_0000184053
Sites
	Active site	20	1	Nucleophile
Experimental info
	Non-terminal residue	28	1

Sequences

	Sequence		Length	Mass (Da)
	P81190 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: B3F1C0C99C9950BE	FASTA	28	2,937
	10 20 SLQAATEWLK ANNQRGFLGE MGAGSNAD

References

[1]	"Identification of the catalytic nucleophile in the cellulase from Schizophyllum commune and assignment of the enzyme to family 5, subtype 5 of the glycosidases." Clarke A.J., Drummelsmith J., Yaguchi M. FEBS Lett. 414:359-361(1997) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH5. Glycoside Hydrolase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.20.20.80. 1 hit.
InterPro	IPR013781. Glyco_hydro_catalytic_dom. [Graphical view]
PROSITE	PS00659. GLYCOSYL_HYDROL_F5. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GUN_SCHCO

Accession

Primary (citable) accession number: P81190

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program