Reviewed, UniProtKB/Swiss-Prot P81138 (CAT1_PENJA)

Names and origin

Protein names	Recommended name:     Catalase     EC=1.11.1.6
Organism	Penicillium janthinellum (Penicillium vitale)
Taxonomic identifier	5079 [NCBI]
Taxonomic lineage	Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Penicillium

Protein attributes

Sequence length	696 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 696	696	Catalase		PRO_0000084925
Sites
	Active site	64	1	By similarity
	Active site	137	1	By similarity
	Metal binding	353	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P81138-1 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: 1A663CD3162C21BB	FASTA	696	77,404
	10 20 30 40 50 60 TASGKLQRKF LDRFAISMGR GVALGKTYGT LGAASRGATL LQDLLFTEII FAFDRERVPE 70 80 90 100 110 120 RAVHARGTGA HGTFLSYEDW SNLTAASFLS AEGKFTPEMT RFSTVSGARG SADTARDVHG 130 140 150 160 170 180 FATRFYVDEG NFDIVGNNIP VFFIWDVIIE PTLMALHAQK PNPRFHLPRG QQDPNRISDN 190 200 210 220 230 240 LTARGDSLAQ GSQISSERGS PKAYSNTEPN KHRSFRLVTD NGKQFQCSNH WQPLQGFIDL 250 260 270 280 290 300 GVEEAWRFPE EGEGYVAENL FESIELLTVG DEELEIQSMS FNNDLRERFN SSEVTKSSVV 310 320 330 340 350 360 RLVPLITQGK LVFNKNIQML FNEVIGAMFQ PGHIVRGVDF TEDPLLQGRL FSYLDTQLNR 370 380 390 400 410 420 HGPNIQQLGF NRPPRAPIHN NNRDGAGEMI DLPPFASFVE TQEWGAKDIK QTAVGQNKFD 430 440 450 460 470 480 QEHRFSHWKF GVNGFVHTRN DDNVTHARGF FTAPERGQQK KRVAAFDRMF TVVGLSVDGQ 490 500 510 520 530 540 QANSDQYADF DAAAGKKVAK AIGVEAPKPN SNYFHPTDVF GEHIAASGTK YGVPEGNTKG 550 560 570 580 590 600 VLLASVNKPA SIAQGAKLQV VASSGDFAEF FISAKQLNMR EVTQGIIPLV PVLKLAKLDL 610 620 630 640 650 660 GKTFRFQLMQ VGNIEELERF GFDLPDLTDK QVDLSAMGMF ETTFRPTSRA AQFEQGKTKL 670 680 690 VKGLQGKNAF MDRALKQPSN NREKIQRFAD RFAVQD

References

[1]	"Complete amino acid sequence of catalase from the fungus Penicillium vitale." Kozlov E.A., Levitina T.L., Bobrovskaia M.T., Gudkova L.V., Latyshko N.V., Radomskii N.F. Bioorg. Khim. 24:163-170(1998) [PubMed: 9612556] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
HSSP	HSSP built from PDB template 1QQW based on UniProtKB P04040.
ModBase	Search...
Protein family/group databases
PeroxiBase	5322. PjaKat01.
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAT1_PENJA

Accession

Primary (citable) accession number: P81138

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	November 25, 2008
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)