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Protein

Gamma-soluble NSF attachment protein

Gene

NAPG

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-BTA-204005 COPII (Coat Protein 2) Mediated Vesicle Transport
R-BTA-6807878 COPI-mediated anterograde transport
R-BTA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-BTA-6811438 Intra-Golgi traffic
R-BTA-6811440 Retrograde transport at the Trans-Golgi-Network

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-soluble NSF attachment protein
Short name:
SNAP-gamma
Alternative name(s):
N-ethylmaleimide-sensitive factor attachment protein gamma
Gene namesi
Name:NAPG
Synonyms:SNAPG
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 24

Organism-specific databases

VGNCiVGNC:31884 NAPG

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002190621 – 312Gamma-soluble NSF attachment proteinAdd BLAST312

Proteomic databases

PaxDbiP81127

Expressioni

Tissue specificityi

Widely expressed.

Gene expression databases

BgeeiENSBTAG00000005158

Interactioni

Subunit structurei

Binds RIP11. Interacts with VTI1A.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006800

Structurei

3D structure databases

ProteinModelPortaliP81127
SMRiP81127
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SNAP family.Curated

Phylogenomic databases

eggNOGiKOG1585 Eukaryota
ENOG410ZYD7 LUCA
GeneTreeiENSGT00390000010109
HOGENOMiHOG000007747
HOVERGENiHBG001648
InParanoidiP81127
KOiK21198
OMAiPYEQAGM
OrthoDBiEOG091G0GNK
TreeFamiTF312872

Family and domain databases

CDDicd15832 SNAP, 1 hit
Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR000744 NSF_attach
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR13768 PTHR13768, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit

Sequencei

Sequence statusi: Complete.

P81127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQKINEGL EHLAKAEKYL KTGFLKWKPD YDSAASEYGK AAVAFKNAKQ
60 70 80 90 100
FEQAKDACLK EAVAHENNRA LFHAAKAYEQ AGMMLKEMQK LPEAVQLIEK
110 120 130 140 150
ASMMYLENGT PDTAAMALER AGKLIENVDP EKAVQLYQQT ANVFENEERL
160 170 180 190 200
RQAVELLGKA SRLLVRGRRF DEAAISIQKE KNIYKEIENY PTCYKKTIAQ
210 220 230 240 250
VLVHLHRNDY VAAERCVRES YSIPGFNGSE DCAALEQLLE GYDQQDQDQV
260 270 280 290 300
AEVCNSPLFK YMDNDYAKLG LSLVVPGGGV KKKAAAPPQA KPEGTAAPAA
310
EEEEDEYAGG LC
Length:312
Mass (Da):34,636
Last modified:June 27, 2006 - v3
Checksum:iACB489517CE36DD9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti214E → R AA sequence (PubMed:8455721).Curated1
Sequence conflicti303E → G in AAI14120 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114119 mRNA Translation: AAI14120.1
RefSeqiNP_001039487.1, NM_001046022.2
UniGeneiBt.47911

Genome annotation databases

EnsembliENSBTAT00000006800; ENSBTAP00000006800; ENSBTAG00000005158
GeneIDi509041
KEGGibta:509041

Similar proteinsi

Entry informationi

Entry nameiSNAG_BOVIN
AccessioniPrimary (citable) accession number: P81127
Secondary accession number(s): Q29RL7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: June 27, 2006
Last modified: March 28, 2018
This is version 109 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health