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Protein

Gamma-soluble NSF attachment protein

Gene

NAPG

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-soluble NSF attachment protein
Short name:
SNAP-gamma
Alternative name(s):
N-ethylmaleimide-sensitive factor attachment protein gamma
Gene namesi
Name:NAPG
Synonyms:SNAPG
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 24

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Gamma-soluble NSF attachment proteinPRO_0000219062Add
BLAST

Proteomic databases

PaxDbiP81127.

Expressioni

Tissue specificityi

Widely expressed.

Gene expression databases

BgeeiENSBTAG00000005158.

Interactioni

Subunit structurei

Binds RIP11. Interacts with VTI1A.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006800.

Structurei

3D structure databases

ProteinModelPortaliP81127.
SMRiP81127. Positions 2-276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SNAP family.Curated

Phylogenomic databases

eggNOGiKOG1585. Eukaryota.
ENOG410ZYD7. LUCA.
GeneTreeiENSGT00390000010109.
HOGENOMiHOG000007747.
HOVERGENiHBG001648.
InParanoidiP81127.
OMAiDACLKEA.
OrthoDBiEOG091G0GNK.
TreeFamiTF312872.

Family and domain databases

CDDicd15832. SNAP. 1 hit.
Gene3Di1.25.40.10. 1 hit.
InterProiIPR000744. NSF_attach.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PANTHERiPTHR13768. PTHR13768. 2 hits.
SUPFAMiSSF48452. SSF48452. 1 hit.

Sequencei

Sequence statusi: Complete.

P81127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQKINEGL EHLAKAEKYL KTGFLKWKPD YDSAASEYGK AAVAFKNAKQ
60 70 80 90 100
FEQAKDACLK EAVAHENNRA LFHAAKAYEQ AGMMLKEMQK LPEAVQLIEK
110 120 130 140 150
ASMMYLENGT PDTAAMALER AGKLIENVDP EKAVQLYQQT ANVFENEERL
160 170 180 190 200
RQAVELLGKA SRLLVRGRRF DEAAISIQKE KNIYKEIENY PTCYKKTIAQ
210 220 230 240 250
VLVHLHRNDY VAAERCVRES YSIPGFNGSE DCAALEQLLE GYDQQDQDQV
260 270 280 290 300
AEVCNSPLFK YMDNDYAKLG LSLVVPGGGV KKKAAAPPQA KPEGTAAPAA
310
EEEEDEYAGG LC
Length:312
Mass (Da):34,636
Last modified:June 27, 2006 - v3
Checksum:iACB489517CE36DD9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti214 – 2141E → R AA sequence (PubMed:8455721).Curated
Sequence conflicti303 – 3031E → G in AAI14120 (Ref. 2) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114119 mRNA. Translation: AAI14120.1.
RefSeqiNP_001039487.1. NM_001046022.2.
UniGeneiBt.47911.

Genome annotation databases

EnsembliENSBTAT00000006800; ENSBTAP00000006800; ENSBTAG00000005158.
GeneIDi509041.
KEGGibta:509041.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114119 mRNA. Translation: AAI14120.1.
RefSeqiNP_001039487.1. NM_001046022.2.
UniGeneiBt.47911.

3D structure databases

ProteinModelPortaliP81127.
SMRiP81127. Positions 2-276.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006800.

Proteomic databases

PaxDbiP81127.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000006800; ENSBTAP00000006800; ENSBTAG00000005158.
GeneIDi509041.
KEGGibta:509041.

Organism-specific databases

CTDi8774.

Phylogenomic databases

eggNOGiKOG1585. Eukaryota.
ENOG410ZYD7. LUCA.
GeneTreeiENSGT00390000010109.
HOGENOMiHOG000007747.
HOVERGENiHBG001648.
InParanoidiP81127.
OMAiDACLKEA.
OrthoDBiEOG091G0GNK.
TreeFamiTF312872.

Gene expression databases

BgeeiENSBTAG00000005158.

Family and domain databases

CDDicd15832. SNAP. 1 hit.
Gene3Di1.25.40.10. 1 hit.
InterProiIPR000744. NSF_attach.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PANTHERiPTHR13768. PTHR13768. 2 hits.
SUPFAMiSSF48452. SSF48452. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSNAG_BOVIN
AccessioniPrimary (citable) accession number: P81127
Secondary accession number(s): Q29RL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: June 27, 2006
Last modified: September 7, 2016
This is version 101 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.