Reviewed, UniProtKB/Swiss-Prot P81113 (ABA3_TRIAB)

Names and origin

Protein names	Recommended name:     Alboaggregin-A subunit 3
Organism	Trimeresurus albolabris (White-lipped pit viper)
Taxonomic identifier	8765 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Scleroglossa › Serpentes › Colubroidea › Viperidae › Crotalinae › Cryptelytrops

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Binds to platelet GPIb/IX receptor system and stimulates agglutination.
Subunit structure	Heterotetramer of the subunits 1, 2, 3 and 4, disulfide-linked.
Subcellular location	Secreted.
Tissue specificity	Expressed by the venom gland.
Sequence similarities	Contains 1 C-type lectin domain.

Ontologies

Keywords
Cellular component	Secreted
Ligand	Lectin
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	sugar binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Alboaggregin-A subunit 3		PRO_0000046710
Regions
	Domain	1 – 125	125	C-type lectin
Amino acid modifications
	Disulfide bond	4 ↔ 15		By similarity
	Disulfide bond	32 ↔ 121		By similarity
	Disulfide bond	98 ↔ 113		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P81113-1 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: CAFA24C098DF3293	FASTA	125	14,799
	10 20 30 40 50 60 GFDCPFGWSS YEGYCYKVYN KKMNWEDAES FCREQHKRSH LVSFHSSGEV DFVVSKTFPI 70 80 90 100 110 120 LRYDFVWMGL SDIWKECTKE WSDGARLDYK AWSGKSYCLV SKTTNNEWLS MDCSRTRYPV CKFXG

References

[1]	"Alboaggregins A and B. Structure and interaction with human platelets." Kowalska M.A., Tan L., Holt J.C., Peng M., Karczewski J., Calvete J.J., Niewiarowski S. Thromb. Haemost. 79:609-613(1998) [PubMed: 9531050] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Venom.

Cross-references

3D structure databases
HSSP	HSSP built from PDB template 1IJK based on UniProtKB P22030.
SMR	P81113. Positions 1-123.
ModBase	Search...
Phylogenomic databases
HOVERGEN	P81113.
Family and domain databases
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. [Graphical view]
Gene3D	G3DSA:3.10.100.10. C-type_lectin-like. 1 hit.
Pfam	PF00059. Lectin_C. 1 hit. [Graphical view]
SMART	SM00034. CLECT. 1 hit. [Graphical view]
PROSITE	PS00615. C_TYPE_LECTIN_1. False negative. PS50041. C_TYPE_LECTIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABA3_TRIAB

Accession

Primary (citable) accession number: P81113

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	November 4, 2008
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)