P81087 (GPX4_PINPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Glutathione peroxidase homolog EC=1.11.1.9 Alternative name(s): Water stress-responsive protein 8/9
Organism	Pinus pinaster (Maritime pine)
Taxonomic identifier	71647 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Coniferopsida › Coniferales › Pinaceae › Pinus › Pinus

Protein attributes

Sequence length	17 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	2 glutathione + H2O2 = glutathione disulfide + 2 H2O.
Induction	By water stress.
Miscellaneous	On the 2D-gel the determined pI of this protein is: 5.6 to 6.7, its MW is: 20 to 23 kDa.
Sequence similarities	Belongs to the glutathione peroxidase family.

Ontologies

Keywords
Biological process	Stress response
Molecular function	Oxidoreductase Peroxidase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular function	glutathione peroxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›17	›17	Glutathione peroxidase homolog		PRO_0000066634
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	17	1

Sequences

	Sequence		Length	Mass (Da)
	P81087 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: 4D245E9B657868C1	FASTA	17	1,943
	10 YKDQGLEILA FPCNQFG

References

[1]	"Water-deficit-responsive proteins in maritime pine." Costa P., Bahrman N., Frigerio J.-M., Kremer A., Plomion C. Plant Mol. Biol. 38:587-596(1998) [PubMed: 9747804] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Needle.
[2]	"Separation and characterization of needle and xylem maritime pine proteins." Costa P., Pionneau C., Bauw G., Dubos C., Bahrman N., Kremer A., Frigerio J.-M., Plomion C. Electrophoresis 20:1098-1108(1999) [PubMed: 10344291] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Needle.

Cross-references

3D structure databases
ModBase	Search...
Protein family/group databases
PeroxiBase	3739. PpGPx06.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000889. Glutathione_peroxidase. IPR012336. Thioredoxin-like_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00255. GSHPx. 1 hit. [Graphical view]
PROSITE	PS00460. GLUTATHIONE_PEROXID_1. Partial match. PS00763. GLUTATHIONE_PEROXID_2. 1 hit. PS51355. GLUTATHIONE_PEROXID_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPX4_PINPS

Accession

Primary (citable) accession number: P81087

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	July 27, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program