P80979 (COX7A_THUOB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Cytochrome c oxidase subunit 7A, mitochondrial EC=1.9.3.1 Alternative name(s): Cytochrome c oxidase subunit VIIa
Organism	Thunnus obesus (Bigeye tuna)
Taxonomic identifier	8241 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Neognathi › Neoteleostei › Eurypterygii › Ctenosquamata › Acanthomorpha › Euacanthomorpha › Holacanthopterygii › Acanthopterygii › Euacanthopterygii › Percomorpha › Perciformes › Scombroidei › Scombridae › Scombrinae › Thunnini › Thunnus

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the cytochrome c oxidase VIIa family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	Cytochrome c oxidase subunit 7A, mitochondrial		PRO_0000221004
Amino acid modifications
	Modified residue	1	1	Blocked amino end (Xaa)
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P80979 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: C111B99419E69A1E	FASTA	15	1,770
	10 XNYVPEAQKL FQAHN

References

[1]	"The subunit structure of cytochrome-c oxidase from tuna heart and liver." Arnold S., Lee I., Kim M., Song E., Linder D., Lottspeich F., Kadenbach B. Eur. J. Biochem. 248:99-103(1997) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Heart and Liver.

Cross-references

Sequence databases
PIR	S77988.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

COX7A_THUOB

Accession

Primary (citable) accession number: P80979

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program