Reviewed, UniProtKB/Swiss-Prot P80974 (COX5B_THUOB)

Names and origin

Protein names	Recommended name:     Cytochrome c oxidase polypeptide Vb     EC=1.9.3.1
Organism	Thunnus obesus (Bigeye tuna)
Taxonomic identifier	8241 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Scombroidei › Scombridae › Thunnus

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Catalytic activity	4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the cytochrome c oxidase Vb family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – ›20	›20	Cytochrome c oxidase polypeptide Vb
Experimental info
	Non-terminal residue	20	1

Sequences

	Sequence		Length	Mass (Da)
	P80974-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 76F1473E1F392BD7	FASTA	20	2,158
	10 20 GTLKGIPTDD EQATGLERRT

References

[1]	"The subunit structure of cytochrome-c oxidase from tuna heart and liver." Arnold S., Lee I., Kim M., Song E., Linder D., Lottspeich F., Kadenbach B. Eur. J. Biochem. 248:99-103(1997) [PubMed: 9310366] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Heart and Liver.

Cross-references

Sequence databases
PIR	S77983.
3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	P80974.
Family and domain databases
InterPro	IPR002124. COX5B. [Graphical view]
PROSITE	PS00848. COX5B_1. Partial match. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

COX5B_THUOB

Accession

Primary (citable) accession number: P80974

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	September 2, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)