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P80964 (PB1_PIG) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Seminal plasma protein pB1
Alternative name(s):
Protein DQH
pAIF-1
OrganismSus scrofa (Pig) [Reference proteome]
Taxonomic identifier9823 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Protein attributes

Sequence length130 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May form a complex with spermadhesin AQN-1 which possesses phosphorylcholine-binding activity.

Subcellular location

Secreted.

Tissue specificity

Component of seminal plasma.

Sequence similarities

Belongs to the seminal plasma protein family.

Contains 2 fibronectin type-II domains.

Ontologies

Keywords
   Biological processFertilization
   Cellular componentSecreted
   DomainRepeat
Signal
   PTMDisulfide bond
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processsingle fertilization

Inferred from electronic annotation. Source: UniProtKB-KW

sperm capacitation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular space

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Ref.2
Chain26 – 130105Seminal plasma protein pB1
PRO_0000019234

Regions

Domain39 – 8345Fibronectin type-II 1
Domain84 – 13047Fibronectin type-II 2

Amino acid modifications

Disulfide bond44 ↔ 68 By similarity
Disulfide bond58 ↔ 81 By similarity
Disulfide bond89 ↔ 115 By similarity
Disulfide bond103 ↔ 130 By similarity

Experimental info

Sequence conflict781W → P AA sequence Ref.2
Sequence conflict841T → Q AA sequence Ref.2
Sequence conflict1161P → T AA sequence Ref.2
Sequence conflict1231Q → R AA sequence Ref.2
Sequence conflict1281R → K AA sequence Ref.2

Sequences

Sequence LengthMass (Da)Tools
P80964 [UniParc].

Last modified January 27, 2003. Version 2.
Checksum: 96DF171A45459DE6

FASTA13015,373
        10         20         30         40         50         60 
MAPRLGIFLL WAGVSVFLPL DPVNGDQHLP GRFLTPAITS DDKCVFPFIY KGNLYFDCTL 

        70         80         90        100        110        120 
HDSTYYWCSV TTYYMKRWRY CRSTDYARCA LPFIFRGKEY DSCIKEGSVF SKYWCPVTPN 

       130 
YDQDRAWRYC 

« Hide

References

[1]"Cloning of complementary DNA encoding the pB1 component of the 54-kilodalton glycoprotein of boar seminal plasma."
Plucienniczak G., Jagiello A., Plucienniczak A., Holody D., Strzezek J.
Mol. Reprod. Dev. 52:303-309(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Isolation and characterization of heparin- and phosphorylcholine-binding proteins of boar and stallion seminal plasma. Primary structure of porcine pB1."
Calvete J.J., Raida M., Gentzel M., Urbanke C., Sanz L., Toepfer-Petersen E.
FEBS Lett. 407:201-206(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 26-130.
Strain: Wild boar.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF047026 mRNA. Translation: AAD11581.1.
PIRA58837.
RefSeqNP_998997.1. NM_213832.1.
UniGeneSsc.579.

3D structure databases

ProteinModelPortalP80964.
SMRP80964. Positions 42-130.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid1148955. 1 interaction.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSSSCT00000003390; ENSSSCP00000003307; ENSSSCG00000003053.
GeneID396806.
KEGGssc:396806.

Organism-specific databases

CTD100034140.

Phylogenomic databases

eggNOGNOG292693.
GeneTreeENSGT00730000111290.
HOGENOMHOG000060267.
HOVERGENHBG007070.
OMADNKCVFP.
OrthoDBEOG75TMF5.
TreeFamTF343543.

Family and domain databases

Gene3D2.10.10.10. 2 hits.
InterProIPR000562. FN_type2_col-bd.
IPR013806. Kringle-like.
IPR016356. Seminal_plasma_PDC-109-like.
[Graphical view]
PfamPF00040. fn2. 2 hits.
[Graphical view]
PIRSFPIRSF002541. Seminal_plasma_PDC-109. 1 hit.
SMARTSM00059. FN2. 2 hits.
[Graphical view]
SUPFAMSSF57440. SSF57440. 2 hits.
PROSITEPS00023. FN2_1. 1 hit.
PS51092. FN2_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePB1_PIG
AccessionPrimary (citable) accession number: P80964
Secondary accession number(s): O46615
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 27, 2003
Last modified: February 19, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families