Reviewed, UniProtKB/Swiss-Prot P80911 (IORB_METTM)

Names and origin

Protein names

Recommended name:
    Indolepyruvate oxidoreductase subunit iorB
      Short name=IOR
    EC=1.2.7.8
Alternative name(s):
    Indolepyruvate ferredoxin oxidoreductase subunit beta

Gene names

Name:

iorB

Organism

Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133)

Taxonomic identifier

79929 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter

Protein attributes

Sequence length	28 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
Catalytic activity	(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.
Subunit structure	Heterodimer of the iorA and iorB subunits.
Biophysicochemical properties	pH dependence: Optimum pH is 10.0. Temperature dependence: Optimum temperature is 80 degrees Celsius.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	indolepyruvate ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›28	›28	Indolepyruvate oxidoreductase subunit iorB		PRO_0000099933
Experimental info
	Non-terminal residue	28	1

Sequences

	Sequence		Length	Mass (Da)
	P80911-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 94FF308CEEC9F55E	FASTA	28	2,894
	10 20 SYNIYVXGVG GQGIXKTSVI IGEAAMNE

References

[1]	"Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum." Tersteegen A., Linder D., Thauer R.K., Hedderich R. Eur. J. Biochem. 244:862-868(1997) [PubMed: 9108258] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

IORB_METTM

Accession

Primary (citable) accession number: P80911

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 5, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)