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Reviewed, UniProtKB/Swiss-Prot P80908 (VORB_METTM)

Last modified November 25, 2008. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesRecommended name:
    Ketoisovalerate oxidoreductase subunit vorB
      Short name=VOR
    EC=1.2.7.7
Alternative name(s):
    2-oxoisovalerate oxidoreductase beta chain
    2-oxoisovalerate ferredoxin reductase subunit beta
Gene names
Name: vorB
OrganismMethanobacterium thermoautotrophicum (strain Marburg / DSM 2133)
Taxonomic identifier79929 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

Protein attributes

Sequence length35 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced ferredoxin + H(+).

Subunit structure

Heterotrimer of the vorA, vorB and vorC subunits.

Biophysicochemical properties

pH dependence:

Optimum pH is 9.7.

Temperature dependence:

Optimum temperature is 75 degrees Celsius.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›35›35Ketoisovalerate oxidoreductase subunit vorB
PRO_0000099955

Experimental info

Non-terminal residue351

Sequences

Sequence LengthMass (Da)Tools
P80908-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: C2AF6C43DE8629BA

FASTA353,670
        10         20         30 
ATQMVXGNTA VIIGAMYAGX DXYFGYPITP ASEIL 

« Hide

References

[1]"Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum."
Tersteegen A., Linder D., Thauer R.K., Hedderich R.
Eur. J. Biochem. 244:862-868(1997) [PubMed: 9108258] [Abstract]
Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases

ModBaseSearch...

Family and domain databases

InterProIPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N.
[Graphical view]
PfamPF01855. POR_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVORB_METTM
AccessionPrimary (citable) accession number: P80908
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 25, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information