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Protein

Ribonuclease 2

Gene
N/A
Organism
Panax ginseng (Korean ginseng)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Two-stage endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.

GO - Molecular functioni

  1. endonuclease activity Source: UniProtKB-KW

GO - Biological processi

  1. defense response Source: UniProtKB-KW
  2. response to biotic stimulus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease, Pathogenesis-related protein

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 2 (EC:3.1.-.-)
OrganismiPanax ginseng (Korean ginseng)
Taxonomic identifieri4054 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsApialesAraliaceaePanax

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Protein family/group databases

Allergomei10131. Pan g 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 153153Ribonuclease 2PRO_0000154156Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP80890.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P80890-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GVQKTETQAI SPVPAEKLFK GSFLDMDTVV PKAFPEGIKS VQVLEGNGGV
60 70 80 90 100
GTIKNVTLGD ATPFNTMKTR IDAIDEHAFT YTYTIIGGDI LLDIIESIEN
110 120 130 140 150
HFKIVPTDGG STITQTTIYN TIGDAVIPEE NIKDATDKSI QLFKAVEAYL

LAN
Length:153
Mass (Da):16,492
Last modified:October 31, 1997 - v1
Checksum:i2E799763E4487E9A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti20 – 201K → I AA sequence (PubMed:12362331).Curated

Cross-referencesi

3D structure databases

ProteinModelPortaliP80890.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei10131. Pan g 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR024949. Bet_v_I_allergen.
IPR000916. Bet_v_I_dom.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF00407. Bet_v_1. 1 hit.
[Graphical view]
PRINTSiPR00634. BETALLERGEN.
PROSITEiPS00451. PATHOGENESIS_BETVI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Primary structures of two ribonucleases from ginseng calluses. New members of the PR-10 family of intracellular pathogenesis-related plant proteins."
    Moiseyev G.P., Fedoreyeva L.I., Zhuravlev Y.N., Yasnetskaya E.G., Jekel P.A., Beintema J.J.
    FEBS Lett. 407:207-210(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Strain: cv. R1.
    Tissue: Callus.
  2. "Proteome of oriental ginseng Panax ginseng C. A. Meyer and the potential to use it as an identification tool."
    Lum J.H.-K., Fung K.-L., Cheung P.-Y., Wong M.-S., Lee C.-H., Kwok F.S.-L., Leung M.C.-P., Hui P.-K., Lo S.C.-L.
    Proteomics 2:1123-1130(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-21.
    Tissue: Root.

Entry informationi

Entry nameiRNS2_PANGI
AccessioniPrimary (citable) accession number: P80890
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1997
Last sequence update: October 31, 1997
Last modified: January 6, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.