P80890 (RNS2_PANGI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Ribonuclease 2 EC=3.1.-.-
Organism	Panax ginseng (Korean ginseng)
Taxonomic identifier	4054 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Apiales › Apiineae › Araliaceae › Panax

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Two-stage endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the BetVI family.

Ontologies

Keywords
Biological process	Plant defense
Cellular component	Cytoplasm
Molecular function	Endonuclease Hydrolase Nuclease Pathogenesis-related protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	defense response Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC response to biotic stimulus Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 153	153	Ribonuclease 2		PRO_0000154156
Experimental info
	Sequence conflict	20	1	K → I AA sequence Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P80890 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 2E799763E4487E9A	FASTA	153	16,492
	10 20 30 40 50 60 GVQKTETQAI SPVPAEKLFK GSFLDMDTVV PKAFPEGIKS VQVLEGNGGV GTIKNVTLGD 70 80 90 100 110 120 ATPFNTMKTR IDAIDEHAFT YTYTIIGGDI LLDIIESIEN HFKIVPTDGG STITQTTIYN 130 140 150 TIGDAVIPEE NIKDATDKSI QLFKAVEAYL LAN

References

[1]	"Primary structures of two ribonucleases from ginseng calluses. New members of the PR-10 family of intracellular pathogenesis-related plant proteins." Moiseyev G.P., Fedoreyeva L.I., Zhuravlev Y.N., Yasnetskaya E.G., Jekel P.A., Beintema J.J. FEBS Lett. 407:207-210(1997) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: cv. R1. Tissue: Callus.
[2]	"Proteome of oriental ginseng Panax ginseng C. A. Meyer and the potential to use it as an identification tool." Lum J.H.-K., Fung K.-L., Cheung P.-Y., Wong M.-S., Lee C.-H., Kwok F.S.-L., Leung M.C.-P., Hui P.-K., Lo S.C.-L. Proteomics 2:1123-1130(2002) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-21. Tissue: Root.

Cross-references

3D structure databases
ProteinModelPortal	P80890.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.30.530.20. 1 hit.
InterPro	IPR024949. Bet_v_I_allergen. IPR000916. Bet_v_I_dom. IPR023393. START-like_dom. [Graphical view]
Pfam	PF00407. Bet_v_1. 1 hit. [Graphical view]
PRINTS	PR00634. BETALLERGEN.
PROSITE	PS00451. PATHOGENESIS_BETVI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNS2_PANGI

Accession

Primary (citable) accession number: P80890

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program