Reviewed,
UniProtKB/Swiss-Prot P80869 (DHG2_BACSU)
Last modified
November 3, 2009.
Version 63.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Glucose 1-dehydrogenase 2 EC=1.1.1.47 Alternative name(s): GLCDH-II Short name=GDH-II General stress protein 74 Short name=GSP74 | ||||
| Gene names |
| ||||
| Organism | Bacillus subtilis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1423 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 258 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. |
| Subunit structure | Homotetramer By similarity. |
| Induction | By heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation. |
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Stress response |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to stressInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro glucose 1-dehydrogenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "A 32 kb nucleotide sequence from the region of the lincomycin-resistance gene (22 degrees-25 degrees) of the Bacillus subtilis chromosome and identification of the site of the lin-2 mutation." Kumano M., Tamakoshi A., Yamane K. Microbiology 143:2775-2782(1997) [PubMed: 9274031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [2] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
| [3] | "First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis." Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M. Electrophoresis 18:1451-1463(1997) [PubMed: 9298659] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-13. Strain: 168 / IS58. |
Cross-references
Sequence databases | |
|---|---|
| AB000617 Genomic DNA. Translation: BAA22244.1. AL009126 Genomic DNA. Translation: CAB12077.1. | |
| PIR | G69755. |
| RefSeq | NP_388165.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1GEE based on UniProtKB P40288. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 938377. |
| GenomeReviews | Gene locus BSU02830 in contig AL009126_GR. |
| KEGG | bsu:BSU02830. |
| NMPDR | fig|224308.1.peg.284. |
Organism-specific databases | |
| SubtiList | BG12761. ycdF. [Micado] |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P80869. |
| OMA | NISSVHQ. |
Enzyme and pathway databases | |
| BioCyc | BSUB224308:BSU0284-MON. |
| BRENDA | 1.1.1.47. 150. |
Family and domain databases | |
| InterPro | IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR19410. ADH_short_C2. 1 hit. |
| Pfam | PF00106. adh_short. 1 hit. [Graphical view] |
| PRINTS | PR00081. GDHRDH. PR00080. SDRFAMILY. |
| PROSITE | PS00061. ADH_SHORT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DHG2_BACSU | ||||||||
| Accession | Primary (citable) accession number: P80869 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| SIMILARITY comments Index of protein domains and families |

Clusters with


