P80869 (DHG2_BACSU) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 81.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Glucose 1-dehydrogenase 2 EC=1.1.1.47 Alternative name(s): GLCDH-II Short name=GDH-II General stress protein 74 Short name=GSP74 | ||||
| Gene names |
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| Organism | Bacillus subtilis | ||||
| Taxonomic identifier | 1423 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 258 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Catalytic activity | Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. |
| Subunit structure | Homotetramer By similarity. |
| Induction | By heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation. |
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Stress response |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Direct protein sequencing Reference proteome |
| Gene Ontology (GO) | |
| Biological process | response to stress Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | glucose 1-dehydrogenase [NAD(P)] activity Inferred from electronic annotation. Source: EC nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "A 32 kb nucleotide sequence from the region of the lincomycin-resistance gene (22 degrees-25 degrees) of the Bacillus subtilis chromosome and identification of the site of the lin-2 mutation." Kumano M., Tamakoshi A., Yamane K. Microbiology 143:2775-2782(1997) [PubMed: 9274031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [2] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
| [3] | "First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis." Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M. Electrophoresis 18:1451-1463(1997) [PubMed: 9298659] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-13. Strain: 168 / IS58. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AB000617 Genomic DNA. Translation: BAA22244.1. AL009126 Genomic DNA. Translation: CAB12077.1. |
| PIR | G69755. |
| RefSeq | NP_388165.1. NC_000964.3. |
3D structure databases | |
| ProteinModelPortal | P80869. |
| SMR | P80869. Positions 1-256. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000004092; EBBACP00000004092; EBBACG00000004084. |
| GeneID | 938377. |
| GenomeReviews | Gene locus BSU02830 in contig AL009126_GR. |
| KEGG | bsu:BSU02830. |
| NMPDR | fig|224308.1.peg.284. |
| PATRIC | 18972125. VBIBacSub10457_0291. |
Organism-specific databases | |
| GenoList | BSU02830. |
Phylogenomic databases | |
| GeneTree | EBGT00070000031907. |
| HOGENOM | HBG750976. |
| OMA | NISSVHQ. |
| PhylomeDB | P80869. |
| ProtClustDB | CLSK886644. |
Enzyme and pathway databases | |
| BioCyc | BSUB:BSU02830-MONOMER. |
Family and domain databases | |
| InterPro | IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| KO | K00034. |
| Pfam | PF00106. adh_short. 1 hit. [Graphical view] |
| PRINTS | PR00081. GDHRDH. PR00080. SDRFAMILY. |
| PROSITE | PS00061. ADH_SHORT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DHG2_BACSU | ||||||||
| Accession | Primary (citable) accession number: P80869 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| SIMILARITY comments Index of protein domains and families |

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